ID A0A1L9S840_9EURO Unreviewed; 756 AA.
AC A0A1L9S840;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA polymerase epsilon subunit B {ECO:0000256|ARBA:ARBA00016011};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN ORFNames=ASPZODRAFT_124125 {ECO:0000313|EMBL:OJJ43317.1};
OS Penicilliopsis zonata CBS 506.65.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicilliopsis.
OX NCBI_TaxID=1073090 {ECO:0000313|EMBL:OJJ43317.1, ECO:0000313|Proteomes:UP000184188};
RN [1] {ECO:0000313|Proteomes:UP000184188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 506.65 {ECO:0000313|Proteomes:UP000184188};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560}.
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DR EMBL; KV878353; OJJ43317.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9S840; -.
DR STRING; 1073090.A0A1L9S840; -.
DR VEuPathDB; FungiDB:ASPZODRAFT_124125; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000184188; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000184188}.
FT DOMAIN 438..713
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 81959 MW; 9FC305EDA2EA6496 CRC64;
MSVTGRASAP TIQRDAADLV PSSSPAFGTP AHPFRITKPG PDRPKTSVLP ILLPVSTLRP
VAFRAFTRKH NLTLSSSTLQ TLANFVGKNC GSGWREEGLA ERVLDEVAKA WKKAGGGVIV
EEGKGASVKT ILQSLEGNII GGRVVTGKTS PDGVVISMKG APSELSTYDS TATAEDKENE
ESDLSLHPRS WMKIVGAYEM PRLLYNVEKK FFEISKSNPT LFPPPSHKTS LFKERYNLIY
QRLLRNEAFQ TALSFSETLP LQRSLGPNQS YKLTPIANLL GRSGTSHLLL GLLSISPTGD
LSLTDLSGSV CLDLSHARII PQDGAWFTPG MIVVVDGIYE EEENVRGSTL GGNSGVGGMI
GGRFVGVTIC GPPCERRDIS LGVKSRPDSA DFNSGGGFGW VDFLGVGSER AQGPRMRKIE
AKCLQSEHPT EASKRLKVAI LSEVNLDDSK TIGALKKVFK SYNDLILSER PLAFILIGNF
IGKGVADGGG QISSIEYKEC FDSLALILSE FPSILRHSTF VFVPGSQDPW ASAFSSGASS
TIPRDAVPEL FTSRVKRAFS TANSESDTPT SAEPAGEAIW TSNPSRLTLF GPVHEITVLR
DDISSRFRRS SVIFDCEAPD PATLEPKDVD MGSALDSATL EDLGETPRLP PKSEDLRSAM
HSARKLVKTI LDQGTMSPFP LSIRPVLWDY SAALHLFPLP TALVLSDSEI SSFCITYEGC
HVMNPGRLVP ENDSNLVRWI EYDVLKNRGK LKEDRF
//
