ID A0A1L9SKF9_9EURO Unreviewed; 1070 AA.
AC A0A1L9SKF9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DUF726 domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPZODRAFT_1754981 {ECO:0000313|EMBL:OJJ47700.1};
OS Penicilliopsis zonata CBS 506.65.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicilliopsis.
OX NCBI_TaxID=1073090 {ECO:0000313|EMBL:OJJ47700.1, ECO:0000313|Proteomes:UP000184188};
RN [1] {ECO:0000313|Proteomes:UP000184188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 506.65 {ECO:0000313|Proteomes:UP000184188};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
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DR EMBL; KV878340; OJJ47700.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9SKF9; -.
DR STRING; 1073090.A0A1L9SKF9; -.
DR VEuPathDB; FungiDB:ASPZODRAFT_1754981; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000184188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184188};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 587..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..652
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1004
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1043..1062
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1070 AA; 117041 MW; 038D7035AF65965B CRC64;
MTSPEGVSPG PIGDRSATFD DPTLPTTGSG HESSPNGPAN DTNDNGKEEI NPGDCSTGKK
TADNNVKAHE EPQEQMLDDF GLPVRVRPRP ARSLSTSSDG SDEFHDVHEE DKRNPEVEGP
EKQERMAGDE NLAAQVDHSD TEKGEEEEED TAPTPAVVEK APVSPKGEDT QRADEPTTPT
AHAHQPNETF SERPLDGSNV EDATSPAPTH SPSQRRHKVH ASEWSHQRLT DQHDAEDSEE
EEEEDGDGGW KDMPALGELD FYDDYGRLVA KGAKEEDDEA VYSGLGGAGK GYTRVQLDED
AQSATSMDED TSYLFKETNG NSAGMEGEEL RDQMSQLQAT KTLLTESQRI AYVGVTRLAM
FQMVREAEKM PSTKQTKRIM QKSEDSLKKW GQSIMARLYH HMDIDAAEQI MIEQLAEHGV
QPEDLIRPLM QNSRVKNPLA GDAPENPVSS PSSPSLKQMS RQSLSSEMEK SSELGSPPPY
EAHEGEDLPE VRTPSQLPTS DNIDIDLRWT VLCDLFLVLI ADSVYDARSR TLLERVGEAM
DVSWLQICRF EKRVIDALEM QESADKETWD ESEHMENRRK MALKKKYMIM GLATVGGGLV
IGLSAGLLAP VIGAGLAAGF TTIGVSGTSA FLGGVGGTAL IASGATLTGG TIGMRASHRR
TGAVQTFEYR PLHNNKRVNL IVTVSGWMTG KVDDVRLPYS TVDPIMGDIY SVLWEPDMLR
SMGDTINILA TEALTQGLQQ VLGSTILVAL MASLQLPIVL TKLSYLIDNP WNVSLARATS
AGLILADSLM NNNLGKRPVT LLGFSLGSRL IFSCLKELAE KGAHGLVQNV YLFGSPMVAN
KDDYLKARSV VAGRFVNGYA SNDWILGYLF RATSGGIMRV AGLAPVEGIP GIENIDVTKL
VNGHMDYRAA MPRLLREVGW EVLSDEFTEI EDPDPEDHAA RQRELIREID EARKEAELKP
EKKRFGLFKR GKLAEKKGWE TYDVNRAEGK SPSSGDDSSE TNPAGSVLFD IDAIRAELAS
EAIQVRELDS TLLGYPPEPQ TSREECQCHN TTTTTSASSR GDAATRLFLR
//
