ID A0A1L9T7X2_9EURO Unreviewed; 950 AA.
AC A0A1L9T7X2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN ORFNames=ASPSYDRAFT_92607 {ECO:0000313|EMBL:OJJ55475.1};
OS Aspergillus sydowii CBS 593.65.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=1036612 {ECO:0000313|EMBL:OJJ55475.1, ECO:0000313|Proteomes:UP000184356};
RN [1] {ECO:0000313|Proteomes:UP000184356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 593.65 {ECO:0000313|Proteomes:UP000184356};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
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DR EMBL; KV878592; OJJ55475.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9T7X2; -.
DR STRING; 1036612.A0A1L9T7X2; -.
DR VEuPathDB; FungiDB:ASPSYDRAFT_92607; -.
DR OrthoDB; 2695287at2759; -.
DR Proteomes; UP000184356; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000184356};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 252..472
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REPEAT 722..755
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 192..219
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 898..932
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 950 AA; 106955 MW; AA215BC6CBC5DC5E CRC64;
MDDAPRSSSP TGEYVALRWE TALAECKRYL NETDYRRLLE FNTCESLLEN LQLLQNNYGT
QTLLLNGKRI ATSLDHYRNF SLALAVASQR NTINAALLWG AVNLAVEVYA AHGTLFSHIV
DMIADMGYDL EMVNSYDWVA AGEPQMERVL VDIVVDVILF WVQTTRFLRR HPIVNLANTA
WPAVCTDFDA TLSRIRKRLA QLKDKAEALS IQKSAMDAKH ASAATTSTAA SDVSLPCTIV
PFPRNTAFCG RESELQSISD ALDQDPENPQ YKILTLVGMG GVGKSQIALS YAFDRADSGV
KAVFWINSET ALTVAESYTE VALRLQLEGA AADGQHLKNR YLVSKWFQQT KVEWLVIFDN
VEDLGVMDGY WPPSSRGSIL ITTRHENIAF EINSDTLRIC PFSTEQGSTL ILKTLHRGSY
SGDEEQASET LSTVLGGLAL AITVAAMQIR LKRMPIQSFV QSYIERGQSL QSSSKIKNIF
YKHSLETVWK TAFDNMDSNA AFIFDTACFC APDNLPMAIF ENPVPEVEHE DDSRHRYNPV
DGLESLLLAS LVSQDESGDI SIHRVLQEEY RKWLGPERQL ASLKKATKLL LGVFPHQKDG
RSMHPVWSIC RKYISHVVML ADIFKRNSYK SLPAEQFHDF IELCSYAAWY LFEISSYKQC
TTFAITAIEA CGSDETLILA HLSQTVGYAE RERGHPKEAG IYLEQAKRIR ERLLPPNHPE
IANIYSSLAG VYVSSGKYDE GLGLFNEAVK IDLTTPYAEH KFIIFRRYLN MATAERLKGN
LDAALEYVDL ATPYILDSFG AETHFDITQI YYRGNIAYDR NDLPQAQSYY EHACRGHVSE
QEFHPAHICA NYKLACTEIK LGKILRAIER LRYAQTLCEV CEASKGDKGD TARIKRKLAE
ALILLDEKDS EAAVLKEEAE NVRRELQGAE FENLPDNDNS YSLLVAHYFR
//
