ID A0A1L9UL21_ASPBC Unreviewed; 977 AA.
AC A0A1L9UL21;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=ASPBRDRAFT_123153 {ECO:0000313|EMBL:OJJ72296.1};
OS Aspergillus brasiliensis (strain CBS 101740 / IMI 381727 / IBT 21946).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=767769 {ECO:0000313|EMBL:OJJ72296.1, ECO:0000313|Proteomes:UP000184499};
RN [1] {ECO:0000313|Proteomes:UP000184499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101740 / IMI 381727 / IBT 21946
RC {ECO:0000313|Proteomes:UP000184499};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
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DR EMBL; KV878683; OJJ72296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9UL21; -.
DR STRING; 767769.A0A1L9UL21; -.
DR VEuPathDB; FungiDB:ASPBRDRAFT_123153; -.
DR OMA; LECITSW; -.
DR OrthoDB; 35663at2759; -.
DR Proteomes; UP000184499; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR PANTHER; PTHR12363:SF53; MRNA TRANSPORT REGULATOR MTR10; 1.
DR PANTHER; PTHR12363; TRANSPORTIN 3 AND IMPORTIN 13; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000184499};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 34..101
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 977 AA; 109643 MW; EF069C75C8FB5595 CRC64;
MASKEGSAGQ SFGAVLAAVT TMSGNVSRSE KEHAHEFLEK FQKSVEAWTI THEMLQSPDV
PVEAKLFAAT TLKGKIVFDL DQLPAESILA LRDSVMNLLV AYAAGPRPIQ TQLCVCLASL
AIQMLDWKDV LPTVGAALGS SAGDCVLEFL KILPEEVTEG RKINLSEEDL DSRTRELLED
NAEQVMHLLI QYAQSSQMSQ LLATASTNPR LLDCITSWMR EIPAAKIVDS PLMDVILKAL
DDDRSFESAV DSMCTLYRDT REVDDSLPII QALYPRLMSL RPKIAEFAEA EDTDAYRGIT
RLFAEAGEAW VVLMARLPTD FRGLVEAVLE CCARDWERDA ISLTFVFWYE LKQYVTLERY
ADARGCFSDV FSSLVDIMVK HLEYPRPEEG ETDLFGGDRE QEEKFRHFRH SMGDVLKDCC
AVIGVNECLT KAYQLIQQWV SKYASQSSDE HVPNWQELEA PLFSLRAMGR MVDPEENVVL
TQVIPLIVQI PNQEKVRFQA IMALARYTEW TAQHPETLEA QLNYVISGFQ HSSPEVVQAA
ALAFKFLGTD CQKLLGGHIA QLHSFYESVL DKLKPASQEE VTEGVAAVVA VQPLEKIYET
MKLFCDPIMA RIMNLANNAK DEEGQRAVAD HLQLITIFIL VVNPYVSPRE ENPAVKYCGE
ILPIMTTIVM NFTSSTPILE RVCRCWRNMI ISYRTAMTPL LPTLAQSLAS GFEASREGCF
LWATDAVVRE FSEGAEFVDP STSHAVFQFY EQQAVAFLRT LNDLPPENLP DVIEDFYRLS
SDAVRYYPKE CVTSSLSVPI FSAALSALTL QQIDPLMATL HYYHDLFSFA FDKPTVSEFT
TADGKSYTNP PEIREAVKQL IASQGQLLTQ HILTGMMFSF PGECFPDASS VMMMLFELMP
EEAGTWLQST LQMLPAGTMK QGEAERLLKG IFDKVHSGEV RKIRVLLQDF TNSYRRRNVA
PREGLGRLEA TRFRFSG
//
