ID A0A1L9UP73_ASPBC Unreviewed; 1140 AA.
AC A0A1L9UP73;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA damage-binding protein 1 {ECO:0000256|ARBA:ARBA00014577};
GN ORFNames=ASPBRDRAFT_122411 {ECO:0000313|EMBL:OJJ73440.1};
OS Aspergillus brasiliensis (strain CBS 101740 / IMI 381727 / IBT 21946).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=767769 {ECO:0000313|EMBL:OJJ73440.1, ECO:0000313|Proteomes:UP000184499};
RN [1] {ECO:0000313|Proteomes:UP000184499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101740 / IMI 381727 / IBT 21946
RC {ECO:0000313|Proteomes:UP000184499};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DDB1 family.
CC {ECO:0000256|ARBA:ARBA00007453}.
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DR EMBL; KV878682; OJJ73440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9UP73; -.
DR STRING; 767769.A0A1L9UP73; -.
DR VEuPathDB; FungiDB:ASPBRDRAFT_122411; -.
DR OMA; HQDFLMR; -.
DR OrthoDB; 226997at2759; -.
DR Proteomes; UP000184499; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 1.10.150.910; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR10644:SF3; DNA DAMAGE-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR Pfam; PF03178; CPSF_A; 1.
DR Pfam; PF10433; MMS1_N; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000184499}.
FT DOMAIN 74..575
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10433"
FT DOMAIN 784..1107
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03178"
FT REGION 150..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1140 AA; 124542 MW; 3069D0803A7AB0E7 CRC64;
MAYVVPIHRA SSIRNALKLH FMNAEEETLV VAKANRLEIY SLTPEGLNLA ASCSLFAKVT
MLARLPAPAN SPTDHLFVGT DRYTYCTLSW NGEKNQVRTE RNYVDISDPS SREAQTGNRC
LIDPSGRFMT LEVYEGVIAV VPIVQLPSKK RGRQVAPPSG PDAPRVGELG EPTTARIDEL
FVRSSAFLHV QSGPPRLALL YEDNQKKVRL KVRALHYSAA TSSTGADAAF EESLDGFSQE
LDLGASHLIP VPAPLGGLLV LGETSIKYVD TDSNEIVSRP LDEATIFVAW EQVDSQRWLL
ADDYGRLFFL MLVLDSNSQV QSWKLDHLGN TARASVLIYL GGGVIFVGSH QGDSQVLRIG
NGSLEVIQTL SNIAPILDFT VMDLGNRTSE SQTHEFSSGQ ARIVTGSGAF GDGTLRSVRS
GVGMEELGVL GEMELITDLF GLQLATKGVY LDTLLVTFVD ETRVFQFNFD GEVEELDSFL
GLSLSENTLL AMNLPGGRIL QVTEQRVLIA DIEGGMVTNE WTPPNQLVIT SASANNDSIV
LVSGGQLMTV LDINNDVRVV AQKDFGADSQ ISGVTVPLSS AGVCIVGFPQ LAKVSVLDLG
RLSELHTTSL GPAGEAFPRS VLVADVLANS PSTLFISMAD GSVITYSFDA SNYSLTGMNR
LILGSEQPTF KKLPRGDGLY NVFATCENPS LIYGSEGRII YSAVNSEGAS RVCHFNSEAY
PGSIAVATRH DLKIALVDKE RTTQIQTLPM GETARRVSYS PSEKAFGIGT IERKLKDGAE
MVQSRFVLAD EIMFRRLDAF DLRPEELVES VIRAEFSAGK DENGRDVYKD RFVVGTAYLD
DETEESIRGR ILVFEIDNGR KLTKVAELPV KGACRALAML GEKIVAALVK TVVIYGVVNN
DFGAMKLEKL ASYRTSTAPV DVTVTGNVIA VADLMKSVCL VEYNEGENGM PDSLTEVARH
FQTVWATGVA CIAKDTFLEA DAEGNLIVLR RNLTGVEEDD KRRLEVTGEI SLGEMVNRIR
PVNIQQLASV TVTPRAFLGT VEGSIYLFAI INPEHQDFLM RLQATMAGKV ESLGNIPFNE
FRGFRSMVRE AKEPYRFVDG ELIERFLTCE PSLQEEIVDL VGMMNVDEVK IMIEALRRLH
//
