ID A0A1L9UXT1_ASPBC Unreviewed; 269 AA.
AC A0A1L9UXT1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA replication complex GINS protein PSF2 {ECO:0000256|ARBA:ARBA00015139, ECO:0000256|PIRNR:PIRNR028998};
GN ORFNames=ASPBRDRAFT_115941 {ECO:0000313|EMBL:OJJ76456.1};
OS Aspergillus brasiliensis (strain CBS 101740 / IMI 381727 / IBT 21946).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=767769 {ECO:0000313|EMBL:OJJ76456.1, ECO:0000313|Proteomes:UP000184499};
RN [1] {ECO:0000313|Proteomes:UP000184499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101740 / IMI 381727 / IBT 21946
RC {ECO:0000313|Proteomes:UP000184499};
RX PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT "Comparative genomics reveals high biological diversity and specific
RT adaptations in the industrially and medically important fungal genus
RT Aspergillus.";
RL Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. Has a role in chromosome segregation.
CC {ECO:0000256|ARBA:ARBA00025163}.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|PIRNR:PIRNR028998}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR028998}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family.
CC {ECO:0000256|ARBA:ARBA00010565, ECO:0000256|PIRNR:PIRNR028998}.
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DR EMBL; KV878680; OJJ76456.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L9UXT1; -.
DR STRING; 767769.A0A1L9UXT1; -.
DR VEuPathDB; FungiDB:ASPBRDRAFT_115941; -.
DR OMA; DSLNCMY; -.
DR OrthoDB; 5487178at2759; -.
DR Proteomes; UP000184499; Unassembled WGS sequence.
DR GO; GO:0000228; C:nuclear chromosome; IEA:UniProt.
DR GO; GO:0032993; C:protein-DNA complex; IEA:UniProt.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:UniProt.
DR CDD; cd11712; GINS_A_psf2; 1.
DR CDD; cd21694; GINS_B_Psf2; 1.
DR Gene3D; 1.20.58.1020; -; 1.
DR Gene3D; 3.40.5.50; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR PANTHER; PTHR12772:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR Pfam; PF05916; Sld5; 2.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR028998};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR028998};
KW Reference proteome {ECO:0000313|Proteomes:UP000184499}.
FT DOMAIN 51..95
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT DOMAIN 148..203
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT REGION 92..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 269 AA; 29645 MW; 91843264C7A76C7A CRC64;
MAFPLPRGIT PPEISFLAEM EMVTVLPRQR LEGLELLGGA VSPLLPPRRT SLPLWLALLL
KRQRRANILP PPWLHPESLE LILEIETQND EYQHAFSPPP PLPGQPAPGD HRRVPLATPR
YTPSGEKYYP APPFLPQNTA RDHIPPGEPP ALPFHWLEVG TMLLEAASDD LVEPDQTRRL
LKELREVRMA KVRAGVDVLD AAAMGGGGVA LTGVGAMELG EGRRFIAGVV DGLRRIGASK
EQARREEMAE EMANGGYDGT QDDDDEMEF
//
