ID   A0A1L9VP13_ASPGL        Unreviewed;       835 AA.
AC   A0A1L9VP13;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Glutaminase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ASPGLDRAFT_24636 {ECO:0000313|EMBL:OJJ85620.1};
OS   Aspergillus glaucus CBS 516.65.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Aspergillus.
OX   NCBI_TaxID=1160497 {ECO:0000313|EMBL:OJJ85620.1, ECO:0000313|Proteomes:UP000184300};
RN   [1] {ECO:0000313|Proteomes:UP000184300}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 516.65 {ECO:0000313|Proteomes:UP000184300};
RX   PubMed=28196534; DOI=10.1186/s13059-017-1151-0;
RA   de Vries R.P., Riley R., Wiebenga A., Aguilar-Osorio G., Amillis S.,
RA   Uchima C.A., Anderluh G., Asadollahi M., Askin M., Barry K., Battaglia E.,
RA   Bayram O., Benocci T., Braus-Stromeyer S.A., Caldana C., Canovas D.,
RA   Cerqueira G.C., Chen F., Chen W., Choi C., Clum A., Dos Santos R.A.,
RA   Damasio A.R., Diallinas G., Emri T., Fekete E., Flipphi M., Freyberg S.,
RA   Gallo A., Gournas C., Habgood R., Hainaut M., Harispe M.L., Henrissat B.,
RA   Hilden K.S., Hope R., Hossain A., Karabika E., Karaffa L., Karanyi Z.,
RA   Krasevec N., Kuo A., Kusch H., LaButti K., Lagendijk E.L., Lapidus A.,
RA   Levasseur A., Lindquist E., Lipzen A., Logrieco A.F., MacCabe A.,
RA   Maekelae M.R., Malavazi I., Melin P., Meyer V., Mielnichuk N., Miskei M.,
RA   Molnar A.P., Mule G., Ngan C.Y., Orejas M., Orosz E., Ouedraogo J.P.,
RA   Overkamp K.M., Park H.-S., Perrone G., Piumi F., Punt P.J., Ram A.F.,
RA   Ramon A., Rauscher S., Record E., Riano-Pachon D.M., Robert V., Roehrig J.,
RA   Ruller R., Salamov A., Salih N.S., Samson R.A., Sandor E., Sanguinetti M.,
RA   Schuetze T., Sepcic K., Shelest E., Sherlock G., Sophianopoulou V.,
RA   Squina F.M., Sun H., Susca A., Todd R.B., Tsang A., Unkles S.E.,
RA   van de Wiele N., van Rossen-Uffink D., Oliveira J.V., Vesth T.C.,
RA   Visser J., Yu J.-H., Zhou M., Andersen M.R., Archer D.B., Baker S.E.,
RA   Benoit I., Brakhage A.A., Braus G.H., Fischer R., Frisvad J.C.,
RA   Goldman G.H., Houbraken J., Oakley B., Pocsi I., Scazzocchio C.,
RA   Seiboth B., vanKuyk P.A., Wortman J., Dyer P.S., Grigoriev I.V.;
RT   "Comparative genomics reveals high biological diversity and specific
RT   adaptations in the industrially and medically important fungal genus
RT   Aspergillus.";
RL   Genome Biol. 18:RESEARCH28.1-RESEARCH28.45(2017).
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DR   EMBL; KV878894; OJJ85620.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1L9VP13; -.
DR   STRING; 1160497.A0A1L9VP13; -.
DR   VEuPathDB; FungiDB:ASPGLDRAFT_24636; -.
DR   OrthoDB; 3715424at2759; -.
DR   Proteomes; UP000184300; Unassembled WGS sequence.
DR   InterPro; IPR014870; GtaA_C.
DR   InterPro; IPR032514; GtaA_central.
DR   InterPro; IPR033433; GtaA_N.
DR   PANTHER; PTHR31987; GLUTAMINASE A-RELATED; 1.
DR   PANTHER; PTHR31987:SF12; PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10910)-RELATED; 1.
DR   Pfam; PF08760; DUF1793; 1.
DR   Pfam; PF16335; DUF4965; 2.
DR   Pfam; PF17168; DUF5127; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000184300};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..835
FT                   /note="Glutaminase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5013358715"
FT   DOMAIN          117..346
FT                   /note="Glutaminase A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17168"
FT   DOMAIN          351..474
FT                   /note="Glutaminase A central"
FT                   /evidence="ECO:0000259|Pfam:PF16335"
FT   DOMAIN          533..576
FT                   /note="Glutaminase A central"
FT                   /evidence="ECO:0000259|Pfam:PF16335"
FT   DOMAIN          582..782
FT                   /note="Glutaminase A C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08760"
SQ   SEQUENCE   835 AA;  92677 MW;  2932E70146E09013 CRC64;
     MRPSLAVLAT AVVQAAVGTA STLTPPVLPL TVRNPYLSTW LGSARDAPWS SWPMFYTGEE
     VGLSVMAQIP GTGSVYPLVG KPHESLGSKV EYPTYLGAKY DASTTNFTYL LDASTSSAAA
     PLEITVSFLS PITPTSTLRQ SIPASYVTVY VDGDINVNIY MDLNGRWVSG DQGSPISWEY
     DVIGLEHSKQ KQALQRWQIR RQNELLLSEI GDRAEWGTLH ITGPADVQYQ SGDAANVRQA
     FAGTGAIKNS NDGEFRPIGD REPVFAFSKS FVSKQQRGKI SDSVTFTIAL IQDPVVQYAS
     ARGITLMRPL WQSWFSSVEA LLQFHYYDFD NAATLASDYS NQLAKDAYLS GAEDYVDIVA
     LSARQVMGAT QFSGTPEDPI LFLKEISSNG NFQTIDVIFP AFPFFMYTNP RWLAYLLEPL
     IEHMLSGQYP NKYTMHDLGT HFPNATGHPD GNDEYMPVEE CGNILIMGLA LVNSLRYDND
     AAASSVWSTQ GMSPKVSDDN AGYFPLDTLQ TLSGIGQQDG KWGGGTQGEL LAKKWVQRSY
     RLWNQWTGYL VEFSLEPANQ LSTDDFAGWL ALQTNLALKG IIGINAMSKL AEVVGEHKDV
     SYYKNISDTY IAKWEELGMS RDGSHAKLSY DWFGSWTTIY NLYADAQLCF HLDGTSLSPK
     GSSYEHQKQE PLGDAPGKNK VGFVPRHIYQ RQSLWYHNVR QKYGLPLDSR HLYTKTDWEF
     FAMAVARRDV RSEILESVAT WINETVTDRP FTDLHETEGD GNFPGPNFFA RPVIGGHFAF
     LALERACGGR AMEGLSFLDD EPAEAKEWTA AAVKAAEEFA TTHYRFDYGS ADEEL
//