ID   A0A1M2VBY5_TRAPU        Unreviewed;      1086 AA.
AC   A0A1M2VBY5;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   SubName: Full=Regulator of nonsense transcripts 2 {ECO:0000313|EMBL:OJT05098.1};
GN   ORFNames=TRAPUB_4163 {ECO:0000313|EMBL:OJT05098.1};
OS   Trametes pubescens (White-rot fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Polyporaceae; Trametes.
OX   NCBI_TaxID=154538 {ECO:0000313|EMBL:OJT05098.1, ECO:0000313|Proteomes:UP000184267};
RN   [1] {ECO:0000313|EMBL:OJT05098.1, ECO:0000313|Proteomes:UP000184267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FBCC735 {ECO:0000313|EMBL:OJT05098.1,
RC   ECO:0000313|Proteomes:UP000184267};
RA   Makela M.R., Granchi Z., Peng M., De Vries R.P., Grigoriev I., Riley R.,
RA   Hilden K.;
RT   "Genome sequence of the basidiomycete white-rot fungus Trametes
RT   pubescens.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJT05098.1}.
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DR   EMBL; MNAD01001491; OJT05098.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M2VBY5; -.
DR   STRING; 154538.A0A1M2VBY5; -.
DR   OMA; DFQHHQI; -.
DR   OrthoDB; 276824at2759; -.
DR   Proteomes; UP000184267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 2.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 2.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184267}.
FT   DOMAIN          496..690
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          705..913
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          942..984
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..45
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        948..976
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1086 AA;  122462 MW;  BF23A2A2541A0F2E CRC64;
     MDAAPNGVAP TKGDDEQSRR AKRAALKELN LSEAGKEPEK ALDSSLKRHT ALIKRTRQSL
     GAENHDQIVK DINSLSLEKY VDEIVGAVVE GISRCKTEKD VWSAVEIISA LHRRFPKTFT
     PALVSSLATS LAAPSRASLA ALSPEQREKE DSTRVSRQRP VLRVCAELAL VGIIRDTPER
     SGGEWIMKTV RDLLSNDPSL SSLPLLLVFL KSYSRPYLGI VPPAASKQIS ASAEPGTLSD
     AASEEASQTN GAFPVLVKEE EELVEKEIRD RFRKMCEGYF DQVAKKLVIE HNRLQEQDRR
     NHEAYIRSGE IFEDRQQAYE KMTKSYEKLL ASCQSLSELL YLPMPTLKTA SQKTESIQIG
     MNTGSSLFGA DVDETAASGG KWEDEEERRF YEEIPDLKDY VPRSVLGLEG DSDVETADGE
     EKERMEKELV EEEFRKLEEE LAEMKIDENG QIVGNGRSKQ VDAKDEEDAD DAPTPTPGTP
     KESPTATPQL APQGPSQLLT ALLARLPDAT NRSLIDQAAV DFAFLNSKAA RKRLVKFLGQ
     IPKSRTDLLP HYSRLIAILA RYLPDVGQDV VAMLDEEFRY LQRKKNVVKE LAEVRLRNTT
     FLSNLTKFGV VPPHVILHMF KVCLDDFSGT NVENLALLLE GCGRFLLRSE DTRVPFGKMI
     ELMRRKQSMA HLDQRQLLLL ENAYYQCNPP ERTARQVKER TPMELFIRHL IYDVLTKKTV
     EKVLRLLRRL DWNAPVVLRT LHKVFTKPWK IKYGQIPLLA ILAYDLQRYH PAFSIGVVDQ
     VMEDIRRGLE TNMYSMNQRR IASAKFLGEL YIYRLISSGI IFDTLWTLVT FGHPEGRPTP
     GQPSQIDMPD DFFRVRIVCV LLDTCGMCFD RGSQLRKLDN FLAFFQLYIL SKGPLPMDVE
     FMLSDSLEAV RPRLVMFKTY EEAAVAVDEM FAVAYQNAGI VRDGGDDSGE ESGEDDDDEK
     ERGQMYEDDE DEQLQPESPV DERAPSPEAV LLKSQHEHIG PTEDDEADFA KELAKLVTDT
     SAESRKIDKK TALALWDTAL PPPVIRKKKH DEYDEDGEVA AGEVAQDAGV MKFTLFTKRG
     NKQQVR
//