ID A0A1M2VJK6_TRAPU Unreviewed; 813 AA.
AC A0A1M2VJK6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Origin recognition complex subunit 1 {ECO:0000256|RuleBase:RU365058};
GN ORFNames=TRAPUB_1382 {ECO:0000313|EMBL:OJT07713.1};
OS Trametes pubescens (White-rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Trametes.
OX NCBI_TaxID=154538 {ECO:0000313|EMBL:OJT07713.1, ECO:0000313|Proteomes:UP000184267};
RN [1] {ECO:0000313|EMBL:OJT07713.1, ECO:0000313|Proteomes:UP000184267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FBCC735 {ECO:0000313|EMBL:OJT07713.1,
RC ECO:0000313|Proteomes:UP000184267};
RA Makela M.R., Granchi Z., Peng M., De Vries R.P., Grigoriev I., Riley R.,
RA Hilden K.;
RT "Genome sequence of the basidiomycete white-rot fungus Trametes
RT pubescens.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the origin recognition complex (ORC) that binds
CC origins of replication. DNA-binding is ATP-dependent, however specific
CC DNA sequences that define origins of replication have not been
CC identified so far. ORC is required to assemble the pre-replication
CC complex necessary to initiate DNA replication.
CC {ECO:0000256|RuleBase:RU365058}.
CC -!- SUBUNIT: ORC is composed of six subunits.
CC {ECO:0000256|RuleBase:RU365058}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU365058}.
CC -!- SIMILARITY: Belongs to the ORC1 family. {ECO:0000256|ARBA:ARBA00008398,
CC ECO:0000256|RuleBase:RU365058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJT07713.1}.
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DR EMBL; MNAD01001131; OJT07713.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M2VJK6; -.
DR STRING; 154538.A0A1M2VJK6; -.
DR OMA; CSFHERL; -.
DR OrthoDB; 118994at2759; -.
DR Proteomes; UP000184267; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd04370; BAH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041083; AAA_lid_10.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF23; ORIGIN RECOGNITION COMPLEX SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17872; AAA_lid_10; 1.
DR Pfam; PF01426; BAH; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00439; BAH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51038; BAH; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU365058};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU365058};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU365058};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU365058};
KW Nucleus {ECO:0000256|RuleBase:RU365058};
KW Reference proteome {ECO:0000313|Proteomes:UP000184267}.
FT DOMAIN 101..224
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..308
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 813 AA; 89224 MW; 911A02B0B159401B CRC64;
MSEPNTPRRR SKRGQPVVAY LPSPSSAVPA EINPSGPLHS RTTTALDLFE DEDHDFDSLD
DLHTHFYQSY SRSTNATSAR APLRTYGRVS RPRNSDADAP TVFNLGDTVL VKTASRIPSV
AVITALWTVE GDDFRPKAPL RVRVHWFVRP GELPKIRARR EFDENEVLYN ISACETLPPS
AILAHCAVSS LPAKRVTVPE DASPDDLFCH LAVDPMRGLY YALDWDAFRL QALAHHSADA
DWPADDVWVV KAQAQAESSA REGAQGPRKR RRVADGDRSE SEDDASGDEF EALLKDESED
EDAEADDVVA ELEPRTPSRK RKRAGTTTPR TPRRTGTASA TTTPRRQRKD ASLAQPTPHS
KAALRKRKKT ALAVRPLPAA AGMLDMDARA MQGLGEDPWL RAMHVLHVAA RPGALPCRET
EYGRVLRAVE ELLEEGSGGC IYISGVPGTG KTATVHAVVR ELKRMAEQNE ANPFAYVEIN
GLKIPEPAAA YGLLWEAVSG HDAARDGHMK IGAKEALRLL SQHFSGAARV GPAGGHACVV
LMDELDQLMT TKQDVVYNFF NWPTLARSKL VVLAVANTMD LPERVMSGRV RSRLGMVRIN
FQPYTTPQLE QIVRARLAGA RLGLPADTPE VLAPDALKFA AMKVSSISGD ARRVLDICRR
TVELVQARKR TARTEDVKAV IKEMQNSPTA AYLRELAFHE RLMLAAVLRC VRKEGVEEIQ
WASVQHQHLV YLNLLGGSGN DADPDPVRRP STDELGQVLD ALLAAHALIC EDGPAVASKA
EGERRVALNL EYAEVERVLG EVGGPKWRNA LNV
//
