ID A0A1M2VSQ4_TRAPU Unreviewed; 544 AA.
AC A0A1M2VSQ4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=TRAPUB_12853 {ECO:0000313|EMBL:OJT10633.1};
OS Trametes pubescens (White-rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Trametes.
OX NCBI_TaxID=154538 {ECO:0000313|EMBL:OJT10633.1, ECO:0000313|Proteomes:UP000184267};
RN [1] {ECO:0000313|EMBL:OJT10633.1, ECO:0000313|Proteomes:UP000184267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FBCC735 {ECO:0000313|EMBL:OJT10633.1,
RC ECO:0000313|Proteomes:UP000184267};
RA Makela M.R., Granchi Z., Peng M., De Vries R.P., Grigoriev I., Riley R.,
RA Hilden K.;
RT "Genome sequence of the basidiomycete white-rot fungus Trametes
RT pubescens.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-
CC O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+);
CC Xref=Rhea:RHEA:67452, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30879, ChEBI:CHEBI:171667, ChEBI:CHEBI:171668;
CC EC=3.1.1.117; Evidence={ECO:0000256|ARBA:ARBA00024511};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:67453;
CC Evidence={ECO:0000256|ARBA:ARBA00024511};
CC -!- SIMILARITY: Belongs to the carbohydrate esterase 15 (CE15) family.
CC {ECO:0000256|ARBA:ARBA00010092}.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJT10633.1}.
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DR EMBL; MNAD01000763; OJT10633.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M2VSQ4; -.
DR STRING; 154538.A0A1M2VSQ4; -.
DR OMA; HWIQQSP; -.
DR OrthoDB; 1463590at2759; -.
DR Proteomes; UP000184267; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000184267};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 27..544
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5009735018"
FT DOMAIN 46..513
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 544 AA; 58478 MW; 6B68182C7308A9BA CRC64;
MTWSHLLSRL SLWAAILPAF SLASSALPNV VDLGYVQYQG NLSFSNTVAY LGVPYAEPPL
GERRFRAPLP LDTARIAREA KGKVVTVNTN PDFCVQGSTG AGEAGGAGSE DCLKVNVYAP
AGAKSGDKLP VLVYIHGGGY VYGNPANWPF DDWINQSPNV VIVSVYYRLD SFGFLTVPEL
ANSALGDLNA GFQDQIQALK WVQQHINAFG GDPSKVTING ESAGGSSIEL HLVAHEGQKL
FSQAIAQSVY RAPLFEPEQL RPLFDFYTAQ AGCGTGSVSV ASRLACLRKA SVSALARAQD
AAMYNFTGHV KGFRPVLDGK LLTEAPTVSL LAGRFADVPV IVGATSNETL SGGTNITAAL
KSYFPGLTDE DLVEYLQQYP ASEFDSDTQR FTVATGDSDV RCGREIIGLA AARKNKAYTY
RYNQAVPTSN STSVAHASEN WMMFRGTSTG FNGTTTFQPQ RPIDKAFASE LIAYWLSFVR
SGDPNAHKLA RAPVWPAYSP ESRRRISLQE GASTDVSGST IEDEPQLETS HCAFVASKAQ
HQQA
//
