ID   A0A1M3FH79_9CELL        Unreviewed;       564 AA.
AC   A0A1M3FH79;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=L-lactate permease {ECO:0000256|RuleBase:RU365092};
GN   ORFNames=BGO37_09125 {ECO:0000313|EMBL:OJV83425.1};
OS   Cellulomonas sp. 73-92.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC   Cellulomonas.
OX   NCBI_TaxID=1895740 {ECO:0000313|EMBL:OJV83425.1, ECO:0000313|Proteomes:UP000184539};
RN   [1] {ECO:0000313|EMBL:OJV83425.1, ECO:0000313|Proteomes:UP000184539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=73-92 {ECO:0000313|EMBL:OJV83425.1};
RA   Kantor R.S., Huddy R.J., Iyer R., Thomas B.C., Brown C.T., Anantharaman K.,
RA   Tringe S., Hettich R.L., Harrison S.T., Banfield J.F.;
RT   "Genome-resolved meta-omics ties microbial dynamics to process performance
RT   in biotechnology for thiocyanate degradation.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Uptake of L-lactate across the membrane. Can also transport
CC       D-lactate and glycolate. {ECO:0000256|RuleBase:RU365092}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU365092};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU365092}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the lactate permease family.
CC       {ECO:0000256|ARBA:ARBA00010100, ECO:0000256|RuleBase:RU365092}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJV83425.1}.
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DR   EMBL; MKTH01000004; OJV83425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M3FH79; -.
DR   STRING; 1895740.BGO37_09125; -.
DR   Proteomes; UP000184539; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015129; F:lactate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003804; Lactate_perm.
DR   NCBIfam; TIGR00795; lctP; 1.
DR   PANTHER; PTHR30003:SF0; GLYCOLATE PERMEASE GLCA; 1.
DR   PANTHER; PTHR30003; L-LACTATE PERMEASE; 1.
DR   Pfam; PF02652; Lactate_perm; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU365092};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365092};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU365092};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU365092};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365092}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        40..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        71..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        115..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        160..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        197..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        251..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        326..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        381..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        419..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        443..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        536..563
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
SQ   SEQUENCE   564 AA;  57933 MW;  1DBAEC4BF15AC2A1 CRC64;
     MFQQVLAPFA HSLLLSALLA ALPLAALFVM LGVFRVKAAY AALVSLGSAV VLAIAVWGMP
     VGQALSATGE GVFYGLFPIL WILVSALWVY NLTVATGWFD ALGRIIRSIS DDPRVLAILI
     AFCFGALLES LAGFGAPVAI SAAMLIAAGM KPVRAAVVSL VANTAPVAFG AMAAPITALA
     GVTGLPVHDL ASMTGRQTPF VALIVPLVLV FLVDGRRGVR ETWPVALVAG GVFGLSQFVV
     SNFLAFEVTD VVASVLTVAA VLLMLRVWQP AVRHDEGGLA TRPAVPTPRG GMPAGPGAAP
     VATLVLEDEA LPTATRRSPG QVLKATAPYL AIIVIFTIAQ LPAVKGWLAV HGTVGFGWPG
     LHVLAPGGKA APNQVFHLDH LKATGTLLFL SGLVTMAIYR ISPKQGALVL GRTLTQLRWT
     IITVASVLGL SFVMNLSGQT TTLGSALAAT GAFFVVLSPA IGWIGVALTG SDTSSNSLFG
     LLQVTAAKSA GLQPVLMAAA NSAAGVMGKM LSVQNLAVAA AAAGMKDGEH VLLRKVIGWS
     LGLAAFVAVI IVLQSTPVLG WMVP
//