ID   A0A1M3GYK2_9PROT        Unreviewed;       515 AA.
AC   A0A1M3GYK2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Exosortase A {ECO:0000313|EMBL:OJW49875.1};
GN   ORFNames=BGO60_06345 {ECO:0000313|EMBL:OJW49875.1};
OS   Thiobacillus sp. 65-1059.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Thiobacillaceae; Thiobacillus.
OX   NCBI_TaxID=1895860 {ECO:0000313|EMBL:OJW49875.1, ECO:0000313|Proteomes:UP000184230};
RN   [1] {ECO:0000313|EMBL:OJW49875.1, ECO:0000313|Proteomes:UP000184230}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=65-1059 {ECO:0000313|EMBL:OJW49875.1};
RA   Kantor R.S., Huddy R.J., Iyer R., Thomas B.C., Brown C.T., Anantharaman K.,
RA   Tringe S., Hettich R.L., Harrison S.T., Banfield J.F.;
RT   "Genome-resolved meta-omics ties microbial dynamics to process performance
RT   in biotechnology for thiocyanate degradation.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OJW49875.1}.
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DR   EMBL; MKUE01000079; OJW49875.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M3GYK2; -.
DR   STRING; 1895860.BGO60_06345; -.
DR   Proteomes; UP000184230; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR013426; EpsH-like.
DR   InterPro; IPR026392; Exo/Archaeosortase_dom.
DR   InterPro; IPR019127; Exosortase.
DR   InterPro; IPR017540; Exosortase-1.
DR   InterPro; IPR014263; Methanolan_biosynth_EpsI.
DR   NCBIfam; TIGR02602; 8TM_EpsH; 1.
DR   NCBIfam; TIGR02914; EpsI_fam; 1.
DR   NCBIfam; TIGR04178; exo_archaeo; 1.
DR   NCBIfam; TIGR03109; exosortase_1; 1.
DR   Pfam; PF11984; DUF3485; 1.
DR   Pfam; PF09721; Exosortase_EpsH; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          311..506
FT                   /note="Methanolan biosynthesis EpsI"
FT                   /evidence="ECO:0000259|Pfam:PF11984"
SQ   SEQUENCE   515 AA;  56590 MW;  77D27562137A4255 CRC64;
     MNALPDSLPS TARNGWLLPA ALTSGVLLLL GAAFWPTVHS MIEVWDRSET FTHGYLVFPI
     SAWLVWRRRD ALAQIRPRPD LRGLLLLAAA GAGWLLADAG SVNVAAQYAF VAMLIAAVWS
     LLGAAFVRAA FFPLMFLLFA VPMGEFLIQP LMGVTADFTV AMLQASGIPV YREGTFFSIP
     SGDWSVVEGC SGLRYLIASV TLGVLYAYLT YRSWQRRLLF SLAAIVVPIF ANSGRAYLIV
     MIAHLSDMKL ALGIDHYIYG WVFFGLVMLL LFWVGSFWRE DEQPEPAVAS GLAPSADGAA
     ARPLLPVAIA ALAVAGLWPA YAGWLDARAL PAMPALQIQA QGGWQPGEDF TGWTPHWIGA
     DRQLRRAYTQ AGRNVLLELN YYVTQRQDAE LINSQNFMIR QKDPLWSNVG ETLATVQIGG
     MARQVRQARL RGSNGQRLLV WQWNLIGRHA TVNDQFAKLS LAFERVLLRR DDGLSVLIAT
     PYEDAEIETA TAALARFAAD MEPAIGRALD RVDGP
//