ID   A0A1M4M3T5_9FIRM        Unreviewed;      1425 AA.
AC   A0A1M4M3T5;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Putative CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:SCG82321.1};
GN   Name=yxcA {ECO:0000313|EMBL:SCG82321.1};
GN   ORFNames=DW1_0712 {ECO:0000313|EMBL:SCG82321.1};
OS   Proteiniborus sp. DW1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Proteiniborus.
OX   NCBI_TaxID=1889883 {ECO:0000313|EMBL:SCG82321.1, ECO:0000313|Proteomes:UP000185208};
RN   [1] {ECO:0000313|EMBL:SCG82321.1, ECO:0000313|Proteomes:UP000185208}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DW1 {ECO:0000313|EMBL:SCG82321.1};
RA   Seilhamer J.J.;
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; FMDO01000013; SCG82321.1; -; Genomic_DNA.
DR   RefSeq; WP_074349255.1; NZ_FMDO01000013.1.
DR   STRING; 1889883.DW1_0712; -.
DR   OrthoDB; 9802715at2; -.
DR   Proteomes; UP000185208; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW   Reference proteome {ECO:0000313|Proteomes:UP000185208}.
FT   DOMAIN          7..255
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          322..576
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          672..891
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
SQ   SEQUENCE   1425 AA;  159613 MW;  C1B8771EDACCDBE9 CRC64;
     MNSVLNVGLD VGSTTVKMVI LDEMTNILYK KYLRHFSDIK NTVISMFEDA KSILERNRIT
     MMITGSGGLS ISKKLDVSFI QEVIACTNTI ERYIPYTDVA IELGGEDAKI TYLGDSVEQR
     MNGTCAGGTG AFIDQMAALL QTDAEGLNNL AKEYRTIYPV ASRCGVFAKT DIQPLLNEGA
     AKEDIAASVL QAVVNQTISG LAQGKPIRGN VAFLGGPLYF MSELRKRFIE TLNLEEDNII
     FPDDSQYYVA LGAALSSRSE EPIPFECLYE RVPDINRIDT DEENKLMPLF KDENEYIEFK
     ERHNKHKVKR VPIEDYKGKA YLGIDAGSTT TKVALIDEEG GLLYSFYGSN MGSPLQSTMD
     ALKDLYNKLN DDIKIVNSAV TGYGEHLIKS ALRIDIGEIE TVAHYKAAEF FLPGVDFVLD
     IGGQDMKSLK IHDGVIDSIM LNEACSSGCG SFIETFANSL NMEVKDFAKA GLSSKNPVDL
     GTRCTVFMNS KVKQAQKEGA DVSDISAGIS ISVIKNALYK VIRLRSVEEL GEKIVVQGGT
     FYNEAVLRAM EIIVDREVVR PDIAGIMGAF GAAIVAKEKY REGYETKLLM KDELKDFTSE
     ISMRRCGLCG NNCLLTINHF SDGREYISGN RCERGAGIEK VENDIPNLYE YKYKRLFSHY
     KPLKVEEAKR GTIGIPRVLN IYEDYPFWFT FFTELGYRVV LSGRSSKKIY ELGMETIPSE
     SVCYPGKMVH GHVIDLLKKG IKKIFYPCIA HNVIEDETAG NHYNCPIVTS YPETINANIE
     ELREDEITFY HPFLPIDDSN RLKKRIYEKL AKEGLSKSEI SNAVDKAYME LEKYKADVRK
     KGEEAIAYIE RNNIKGILLA GRPYHIDPEI NHGIPEMIKS YGFAVISEDS ICHLAEVERP
     IRVVDQWVYH SRMYRAATYV AKRNDIELVQ LNSFGCGLDA VTTDQVQEIL ERFGKIYTVI
     KIDEINNLGA VRIRIRSLMA AIAEREKRNF EPVELYGIQK RVIFTEKMKK THTILSPQMS
     PIHFQFLQTG FRKAGYNIEI LPSVDKKAID EGLRYVHNDA CYPSIITVGQ IMEALKSGKY
     DLNNTSVIIS QTGGGCRATN YIAFIRKALK DAGMGHVPVI SLNAGGLEKN PGFKVTIPIL
     NNLLMGMIYG DLLMRVLYKV RPYEKVPGSA NKLYEYWVEK CKDALENGTR KDFIRNIYGI
     VEDFDSLEIH EDMIKPKVGV VGEILVKFHP TANNDIVGIL ESEGAEAVVP DLTDFFLYTA
     FNSKTKYREL SGSYKGSLFA GVAIEAIEYY RKDMKKALAN SKRFTPPVSI EELAEGAEKH
     LSLCNQTGEG WFLTAEMVEL INSGVPNIVC LQPFACLPNH ITGKGMIKEL RRAYPESNIA
     AIDYDPGASE VNQLNRIKLM LSVAFKNLEK EIELKGHQQE AALTH
//