ID   A0A1M4N6L3_9RHOB        Unreviewed;       575 AA.
AC   A0A1M4N6L3;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Type I restriction modification DNA specificity domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=KARMA_2963 {ECO:0000313|EMBL:SCM68736.1};
OS   Donghicola eburneus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Donghicola.
OX   NCBI_TaxID=393278 {ECO:0000313|EMBL:SCM68736.1, ECO:0000313|Proteomes:UP000184085};
RN   [1] {ECO:0000313|Proteomes:UP000184085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wibberg D.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-I restriction system S methylase
CC       family. {ECO:0000256|ARBA:ARBA00010923}.
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DR   EMBL; FMJB01000059; SCM68736.1; -; Genomic_DNA.
DR   RefSeq; WP_072707590.1; NZ_FMJB01000059.1.
DR   AlphaFoldDB; A0A1M4N6L3; -.
DR   Proteomes; UP000184085; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.220.20; DNA methylase specificity domains; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR003356; DNA_methylase_A-5.
DR   InterPro; IPR000055; Restrct_endonuc_typeI_TRD.
DR   InterPro; IPR044946; Restrct_endonuc_typeI_TRD_sf.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF01420; Methylase_S; 1.
DR   Pfam; PF02384; N6_Mtase; 1.
DR   SUPFAM; SSF116734; DNA methylase specificity domain; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184085};
KW   Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT   DOMAIN          231..361
FT                   /note="DNA methylase adenine-specific"
FT                   /evidence="ECO:0000259|Pfam:PF02384"
FT   DOMAIN          378..554
FT                   /note="Type I restriction modification DNA specificity"
FT                   /evidence="ECO:0000259|Pfam:PF01420"
SQ   SEQUENCE   575 AA;  62937 MW;  A64B65EFCE200106 CRC64;
     MKIEDLLHQT RGTLAPEEAF SLLIEVAAKM KQGNFALENL REPHMARAAG LLPALEGSAK
     ILLSADPDVR LSVIAKFMTM GNRVQDQLGV IQGDAADQLL DLIDGAESVR FSFGPSLFSC
     LIYGRRLVAA GKSPKLTFCS FVQNECRFME DAAQVLDLEE VISVECKFPW ARESLSEAAV
     EVMMPPFGLH IRDIAEVPAR TLALLGIDEG RAARVNGETV SIADALENTR ARVIIAVSEG
     ELFRMVGAEP VARRALIESG RLKAVLGVPS GMMFANTFIK TSLIVMSPSL STSNEVRFID
     LGHEALSQKG RRGRAEILKG TSWRDAIKAP VSDDRSLARD VTHDEIKENK FVLVSDRYLN
     IGTREQIDAL LAQSDVAPLE DIVELVRSVT IPADNDGEYG LLEAAPSDVN ARGYVGEPKR
     EITVDRAKYN KACKQQIRPG DVLLSIKGTV GVVALVPDDV PGEGARRIWT AGQAMMILRP
     KARVKMSSLA LYEYLSNETV QEYIKSIAGG AAVQTIAMKD LKGFAIPMPD EETVAALEEN
     FAERQKIFDE IDALKMKLED VRGRGWPHLQ LRAQS
//