ID A0A1M4S1A3_9ACTO Unreviewed; 365 AA.
AC A0A1M4S1A3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Laci bacterial regulatory protein hth signature {ECO:0000313|EMBL:SHE25968.1};
GN ORFNames=ACGLYG10_2205 {ECO:0000313|EMBL:SHE25968.1};
OS Actinomyces glycerinitolerans.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1892869 {ECO:0000313|EMBL:SHE25968.1, ECO:0000313|Proteomes:UP000184291};
RN [1] {ECO:0000313|Proteomes:UP000184291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Strepis N.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQTT01000012; SHE25968.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M4S1A3; -.
DR STRING; 1892869.ACGLYG10_2205; -.
DR Proteomes; UP000184291; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000184291};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 27..55
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 30..84
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 365 AA; 38742 MW; A20D28173B63741A CRC64;
MARLNPYQVP PRGGSISRFP FRMGIVQQRI TLADIAEQAG VSTATVSRVL NGKSNVAEAT
RRQVLVALDL LGYERPESLR QTSKGLVGLI VPELTNPIFP LYAQEIEQLL APSGHTPLLC
TQTPGGTSED EYIEMLVDRG VAGIIFVSGR HSDTGGDVTR YQRLRDRGVP LVTVNGNAST
IKVPGFATDD RAAARMAVDH LASLGHTRIG LATGPGRMVP AQRKTAGYED GMRANLPDQP
LRIVETLYTY EGGASAAGRL LEQDCTGIIC GSDIMALGVI SGVRAAGKHV PQDVSVIGYD
DSPLIPMMNP PLTTVRQPVA AICRAAVTTL LSAIAGEHPA DTELLFKPDL IVRGSTAPAP
HAMVS
//
