ID A0A1M4S2B6_9ACTO Unreviewed; 270 AA.
AC A0A1M4S2B6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN ORFNames=ACGLYG10_2616 {ECO:0000313|EMBL:SHE26365.1};
OS Actinomyces glycerinitolerans.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1892869 {ECO:0000313|EMBL:SHE26365.1, ECO:0000313|Proteomes:UP000184291};
RN [1] {ECO:0000313|Proteomes:UP000184291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Strepis N.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; FQTT01000014; SHE26365.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1M4S2B6; -.
DR STRING; 1892869.ACGLYG10_2616; -.
DR OrthoDB; 9815856at2; -.
DR Proteomes; UP000184291; Unassembled WGS sequence.
DR GO; GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
DR CDD; cd11642; SUMT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006366; CobA/CysG_C.
DR NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SHE26365.1};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000184291};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 32..234
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 270 AA; 27896 MW; 3955173C4C64A07E CRC64;
MSRTSTAPGI GGRPAQEVES VPDTDRLGTG WVALIGGGPG DPGLVTVRGL DLLRRADVVV
VDRLAPRQLL EAAGPGTEVI DVGKRPGHHL LPQEQINAVL VERARAGQRV ARLKGGDPYV
LGRGGEEAAA CRAAGVIVEI VPGVTSAIAV PAAAGIPVTH RGLARGFSVV TAHEELVSTV
PARRDHTLIL LMGVAHLRRS ATILLQAGAE PDTPAAIVER GFLPDQRVTT TVLRCLPDVA
TEVGVTAPAV IVIGDVVTVS PAWNTRVVPG
//
