ID   A0A1M4SI66_9BACT        Unreviewed;      1065 AA.
AC   A0A1M4SI66;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SHE31890.1};
GN   ORFNames=SAMN05444008_101135 {ECO:0000313|EMBL:SHE31890.1};
OS   Cnuella takakiae.
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Cnuella.
OX   NCBI_TaxID=1302690 {ECO:0000313|EMBL:SHE31890.1, ECO:0000313|Proteomes:UP000184368};
RN   [1] {ECO:0000313|EMBL:SHE31890.1, ECO:0000313|Proteomes:UP000184368}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 26897 {ECO:0000313|EMBL:SHE31890.1,
RC   ECO:0000313|Proteomes:UP000184368};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQUO01000001; SHE31890.1; -; Genomic_DNA.
DR   RefSeq; WP_073039036.1; NZ_MTFE01000010.1.
DR   AlphaFoldDB; A0A1M4SI66; -.
DR   STRING; 1302690.BUE76_23555; -.
DR   OrthoDB; 9758234at2; -.
DR   Proteomes; UP000184368; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF8; CATION EFFLUX PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184368};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        427..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        462..485
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        531..550
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        875..895
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        902..922
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        928..949
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        978..997
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1009..1030
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1065 AA;  115312 MW;  0F3A99F4D50FD905 CRC64;
     MNIIRLALRK PIAVMVMVLA IGYFSFLVVK KINVDIFPKI ESPAIYIAMP YGGLTPSYMD
     GFMANEFQKV LVFVSGVKDI EFKSIQGFTL MKLSFYAGTD MAQAAAEVST QVSRAMGFLP
     PGAVPPQVVR FDGSSLPIGQ LVFESDKRSI GEVQNLVMTR IRPQFVSIPG ITAPAPFGGN
     VRSIVVKVNP GLMQSYGLSE EQVMTAIAKN NLPSPAGNIR IGDKNYMSPV NSMAKGPEEF
     LNLPVRTEGA ATVFIRDIAT VEDGADVTTG YAVINGKRSV YLPVIKKADA STLKVVESLK
     SSLPMLKESL PDDVNIDYVF DQSVYIERSI ENLIHEGILG AILTGLMVLL FLGDNRGALI
     VVLTIPISIL TAVLLLSAFG QTINMMTLSG LALAIGILVD EATVTIENIH QHFEKGKYKS
     RAIVDALLEI SIPKLLILLC ILAVLLPSFI MTGIPKDMFL PLSLAVGFSM IASFVFSQTF
     VPVMANWLMK IKKHKHHVDK NGKMKLTRFE KFKRRYLVLT RSFQRNRKTV VATYAIVVGA
     LVAVGFMSIG TDIMPPSGTT DLQVRITAPA GTRIEKTEEY LHSVMDIVSA EAGAEAVTIT
     SAFVGTQPSG TAINPIFLFT SGSQEAVLQI SLDKNGLPNS IDAIKEGIRK SVAEKLPELQ
     LSFEPIELVE KIMSSGTNTP VQIRVAAGQL AQAAVYAKKI EANLKQVHFL RDVRMEEAVH
     YPSLQIEVDR ERAAQFGLTM QDVTQVMTMA TSSTRFVNKT LWRDPKSGLI FQVQLQVPEA
     SMQTINDIKM LPLKAGQARP ILDDVSSISA GMEPGQVNRQ GANRYVTVAA NIHQKDLGAA
     AEAVKKAIEG AGERPKGVLV STQGQLTLLA DTLDGLKTGL VIAIVVIFLL LAAYYQSFAL
     SAMILSVIPA VIAGSLLVLL AFGSTLNLQS YMGIIMSVGV SVSNAFLLAD HAERSRFKYK
     LDTGVSAILS ASSRLRPIIM TTLAMIAGMV PMAIGFGEGG EQVAPLGQSV IGGLLMSTLT
     TLLVMPHLFV MVRKKATLQS ASLDPDDSES RFFKKETLIL EPQKF
//