ID A0A1M4SQG0_9FIRM Unreviewed; 615 AA.
AC A0A1M4SQG0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=TrkA-C domain-containing protein {ECO:0000313|EMBL:SHE34483.1};
GN ORFNames=SAMN02746064_00342 {ECO:0000313|EMBL:SHE34483.1};
OS Alkalibacter saccharofermentans DSM 14828.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Alkalibacter.
OX NCBI_TaxID=1120975 {ECO:0000313|EMBL:SHE34483.1, ECO:0000313|Proteomes:UP000184251};
RN [1] {ECO:0000313|EMBL:SHE34483.1, ECO:0000313|Proteomes:UP000184251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14828 {ECO:0000313|EMBL:SHE34483.1,
RC ECO:0000313|Proteomes:UP000184251};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FQTU01000001; SHE34483.1; -; Genomic_DNA.
DR RefSeq; WP_073269324.1; NZ_FQTU01000001.1.
DR AlphaFoldDB; A0A1M4SQG0; -.
DR STRING; 1120975.SAMN02746064_00342; -.
DR OrthoDB; 9765532at2; -.
DR Proteomes; UP000184251; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR PANTHER; PTHR43652:SF1; CATION TRANSPORTER-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS01271; NA_SULFATE; 1.
DR PROSITE; PS51202; RCK_C; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184251};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..312
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 318..402
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 615 AA; 68453 MW; 7601B754E390AB19 CRC64;
MLTDIQLVFI ILALTILCFL TPRFRSDMVA LSSLMALYLT GLLTVQEALS GFANSVVIMI
AALFVVGEGI FQTGLAERAG NLLVKHTGNS EFKMTIFMML LVALLSGFIS NTGTIAIFIP
MVVSFCRKMQ IHPGKLLMPL AFTSSMGGTL TLIGTAPNLL ASQTLVDYGY DSLKFVSFTA
IGAIVLVVGI TYLWFIGRKM LDRPHENDAH SANQSEDIDL LKEYNISQYI HHINIPEGFE
DEGKTLRDIK WRSVYNITVL EVIRKPAKKQ FLLPKSTLRF LPGADYSPKS GDYLIVYGHK
EAIYKLIEDK GVEITEENDS GDFMLEKARL AEVILTPQSA FINQSIEDIR FRDKYDLTIL
ALKHQYKDAR RPDQNEMLLY GDTMLVYGEW KDINLLHEEK RDTVVLSHVR KPAAALPHPG
RSFLAGLILI WMIFMMVFEV LPTVITVIMT ALIIVFTRCV RQTDHAYRSI NWHTIILIAC
MLPMATALEK TGGIEYISER LVAGLGDVGP LAVMAGLYII ASVFSQFISN TATAVLLYPV
AIMTSQNLVV SPYPMVMAVA FAASMAFATP VATPPNAMVM AAGKYKFMDF MRVGAPVQLI
TAIFIILFLP IFFPF
//
