ID A0A1M4SV23_9FIRM Unreviewed; 443 AA.
AC A0A1M4SV23;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SHE36055.1};
GN ORFNames=SAMN02745190_00260 {ECO:0000313|EMBL:SHE36055.1};
OS Schwartzia succinivorans DSM 10502.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Schwartzia.
OX NCBI_TaxID=1123243 {ECO:0000313|EMBL:SHE36055.1, ECO:0000313|Proteomes:UP000184404};
RN [1] {ECO:0000313|EMBL:SHE36055.1, ECO:0000313|Proteomes:UP000184404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10502 {ECO:0000313|EMBL:SHE36055.1,
RC ECO:0000313|Proteomes:UP000184404};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC ECO:0000256|PIRNR:PIRNR005353}.
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DR EMBL; FQUG01000002; SHE36055.1; -; Genomic_DNA.
DR RefSeq; WP_072934377.1; NZ_FQUG01000002.1.
DR AlphaFoldDB; A0A1M4SV23; -.
DR STRING; 1123243.SAMN02745190_00260; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000184404; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR026033; Azg-like_bact_archaea.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PIRSF; PIRSF005353; PbuG; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW Reference proteome {ECO:0000313|Proteomes:UP000184404};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 443 AA; 46839 MW; 6CC454961B8E3BC7 CRC64;
MATQSQGGML NRLFHLNEKK TNVQTEMIAG FTTFISVAYI LFVNPNILAD AGIPKEAAIA
ATIWVAALTT TFMGLYANYP VALAPGMGLN AFFTYYVVGT LHLPWQVALG AVFFSGVFFF
ILTVGGVRQA IIRAVPENLK HAITVGIGMF IAFIGFRGTG LIVADKATYI TLGHVAEPTT
LLALVGLLLT GVLIVRGVKG SILIGIAVIT LASMFMGLSP VPHGIGDIMS FDIPSMEATF
GQFDIRGAWE FGIFSIIFTF TVVELFDNMG TLIGLTTKAN LVKEDGEIEN LDRALTTDAI
GTMLSALFGT STVTSYLESA AGIAEGGKTG LTAVTVAVLF VVSLVFAPLI GLVPAFATSP
ALIIVGALMI SEVRNVSFGA FDDALPAFLT IIMMPLTSSI ANGFAFGFVS YVVMKVGAGK
IKEISPIMWI IALAFLVNLE LRG
//
