ID   A0A1M4SX83_9THEO        Unreviewed;       786 AA.
AC   A0A1M4SX83;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=DNA excision repair protein ERCC-2 {ECO:0000313|EMBL:SHE36851.1};
GN   ORFNames=SAMN02746089_00153 {ECO:0000313|EMBL:SHE36851.1};
OS   Caldanaerobius fijiensis DSM 17918.
OC   Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Caldanaerobius.
OX   NCBI_TaxID=1121256 {ECO:0000313|EMBL:SHE36851.1, ECO:0000313|Proteomes:UP000184088};
RN   [1] {ECO:0000313|EMBL:SHE36851.1, ECO:0000313|Proteomes:UP000184088}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17918 {ECO:0000313|EMBL:SHE36851.1,
RC   ECO:0000313|Proteomes:UP000184088};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC       {ECO:0000256|ARBA:ARBA00038058}.
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DR   EMBL; FQVH01000001; SHE36851.1; -; Genomic_DNA.
DR   RefSeq; WP_073341176.1; NZ_FQVH01000001.1.
DR   AlphaFoldDB; A0A1M4SX83; -.
DR   STRING; 1121256.SAMN02746089_00153; -.
DR   OrthoDB; 9803913at2; -.
DR   Proteomes; UP000184088; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.275.30; -; 1.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006555; ATP-dep_Helicase_C.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR045028; DinG/Rad3-like.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR006554; Helicase-like_DEXD_c2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR   PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR   PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF06733; DEAD_2; 1.
DR   Pfam; PF13307; Helicase_C_2; 1.
DR   SMART; SM00488; DEXDc2; 1.
DR   SMART; SM00491; HELICc2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184088}.
FT   DOMAIN          179..425
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51193"
SQ   SEQUENCE   786 AA;  91377 MW;  B55EB271C67E9996 CRC64;
     MKKGIINISV RELVEFVLMS GDITSGFSTG SGAIEGIKGH KLLQKAQGYK SEVTVRHSIE
     VDDIKIEITG RIDGVIEEES SVVIDEIKTV EKDLEEIDDG NDLHWGQAKC YAYIYAVQNN
     LAYIDVQLTY YSIGTREIKR FRRRCSFDEL KLFFYEVISK YVEWAKLLRD WAYIRDKSIK
     ELSFPYASYR KGQRKLAVAT YNAIKNGKKL FVQAPTGIGK TIATIFPAVK AIGEGLTSKV
     FYLTAKNTNI TVAEETLDKL SQGGLRIKRL TITAKEKICF NGEITCDPEK CDYAKGHFDR
     VKDAIRDIFK EDAFTREKIE IYARKHKVCP FEFSLDLSLW SDFIMCDYNY VFDPKAYLRR
     HFDNKTDYVF LIDEAHNLVD RAREMFSAEL YKKKILHLKK TIKNELPDIA KSLFKMNKYM
     LKLRKACGEG NFFIQKEVPD EIYGILRNFI EKAELWLKKE INAPFRQELL KLYFDIYTFI
     RIYELYDEKY VTYAEKIEDE IKLKIFCVDP SKLINKALNR GKAAIFFSAT LTPIDYFQQM
     FGCADDEVCS RLKLASPFPR ENMCLLIDNS VSTKYDERKL SYSVIPDIIF ASISGKRGNY
     LVFFPSYEYM YNVYERFVEK YPNIKTLRQD PNMTEGERRE FLNYFCENNE CYTIGFAVMG
     GIFGEGIDLT GDRLLGVIII GVGLPQICFE RDIIKDYYQK LNGKGFEYAY IYPGMNRVLQ
     AAGRVIRTER DRGIILLIDE RFTHWIYKRL FPPEWSPKIV KDENEIKAQV VKFWNEAGLV
     HKSGTT
//