GenomeNet

Database: UniProt
Entry: A0A1M4UC27_9ACTN
LinkDB: A0A1M4UC27_9ACTN
Original site: A0A1M4UC27_9ACTN 
ID   A0A1M4UC27_9ACTN        Unreviewed;       314 AA.
AC   A0A1M4UC27;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   13-FEB-2019, entry version 9.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=SAMN02745225_00921 {ECO:0000313|EMBL:SHE54206.1};
OS   Ferrithrix thermotolerans DSM 19514.
OC   Bacteria; Actinobacteria; Acidimicrobiia; Acidimicrobiales;
OC   Acidimicrobiaceae; Ferrithrix.
OX   NCBI_TaxID=1121881 {ECO:0000313|EMBL:SHE54206.1};
RN   [1] {ECO:0000313|EMBL:SHE54206.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19514 {ECO:0000313|EMBL:SHE54206.1};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; FQUL01000009; SHE54206.1; -; Genomic_DNA.
DR   UniPathway; UPA00121; UER00345.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Lyase {ECO:0000256|RuleBase:RU361254};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254}.
FT   DOMAIN        9    189       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      203    278       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   SITE        182    182       Essential for prephenate dehydratase
FT                                activity. {ECO:0000256|PIRSR:PIRSR001500-
FT                                2}.
SQ   SEQUENCE   314 AA;  34570 MW;  F7DA63581B34534B CRC64;
     MVNEFSEPTV AYLGPRGTFT EEALFSLDDL KGYRAVPLGS FKEVLERTEA GEFDLGFLPI
     ENSIEGTVLA TLDPMVFEHH LLIQREVELE IHQNLLVKPG TERTEIKTII SYSHATAQCA
     NYIKHNLPGV TISTADSTAQ AAQIVAESDD HTLAAIGPLV AAQIYGLWVE TEQIEDFANN
     KTRFVLLSRT GVPEMTGCDK TSIVCFQLAD RPGSLLGILE HFARRSINLS KLESRPAKSV
     MGEYCFIIDF EGHIRDEPVA ECLEAISDSQ AGVKFLGSYP RVPVSSLKDI EKNSVSRVGY
     VGKGWVRELL NPLG
//
DBGET integrated database retrieval system