ID A0A1M4UM03_STRHI Unreviewed; 838 AA.
AC A0A1M4UM03;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Vancomycin resistance protein YoaR, contains peptidoglycan-binding and VanW domains {ECO:0000313|EMBL:SHE57688.1};
GN ORFNames=SAMN05444320_101476 {ECO:0000313|EMBL:SHE57688.1};
OS Streptoalloteichus hindustanus.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Streptoalloteichus.
OX NCBI_TaxID=2017 {ECO:0000313|EMBL:SHE57688.1, ECO:0000313|Proteomes:UP000184501};
RN [1] {ECO:0000313|EMBL:SHE57688.1, ECO:0000313|Proteomes:UP000184501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44523 {ECO:0000313|EMBL:SHE57688.1,
RC ECO:0000313|Proteomes:UP000184501};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQVN01000001; SHE57688.1; -; Genomic_DNA.
DR RefSeq; WP_073479637.1; NZ_FQVN01000001.1.
DR AlphaFoldDB; A0A1M4UM03; -.
DR STRING; 2017.SAMN05444320_101476; -.
DR Proteomes; UP000184501; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007391; Vancomycin_resist_VanW.
DR InterPro; IPR022029; YoaR-like_PG-bd.
DR PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR Pfam; PF12229; PG_binding_4; 1.
DR Pfam; PF04294; VanW; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184501};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 277..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 488..585
FT /note="YoaR-like putative peptidoglycan binding"
FT /evidence="ECO:0000259|Pfam:PF12229"
FT REGION 1..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 88426 MW; 88F37B13AA769E34 CRC64;
MPEEQRRESE AERTVVLSAV TGRPSGTTPA DRPGGPSARS SDITPDEEFR NHTVAQITPG
QPEVGHRHPP VVDPADQPTV AHEPVSEQPV PDRPQSEPTI RHRLDADDPD PTTRASAEQP
TVAWPTPADH ASLAARVDQP TERTAIVRPF VDQPTLTSPT PAPSAAAPST GAAEPAAERT
TVVQPVVPRG EATEVVAEQD GPVEGSGERT VVLAPVATAA ATTVAAAAAE PETRSAGTAT
ALLDPPAEPA AERDADRTEP PPGGETRADR RRQARRAGIV AGAVGGALVL LYGLDLALSQ
GSVPRGVTVA GVEVGGMEPA AAEQKLREQI GPRLGKPVQV RAGDVQASLD PKSSGLELDW
ARTIADAGEQ SLNPWTRLTS FFSTREVGVA SRTDQTKLTA ALEALRPKTD REAAEGTIRF
EGVKPVAVDP KPGQKLDVPQ AVNELLPHWA DGTTLSLPVT TVPVKTTPDG VRKALDEIAK
PAVSGPVTVQ GEGKNGTLEP AVIASALTFQ PGDNGGLTPK LDENKITEAV RPQLKDTEQP
GKDAKISLAS GAPVVEPSQE GRGIDYAKTF APLPDVLRRA QDRTVKAEYG KQPAKFTTEQ
ANQLGVKEVI AEFKTGGFAA DSGHNIRLAA EKMNGAVVKP GETFSMNRQT GPRTAATGYI
GAGIINDGKP DRAVGGGVSQ MATTLYNAAY YAGMTDAGHT PHSYWINRYP KGREATVFQN
PDGSSVIDLQ FRNDTKTGVL IETIWTPSSI TVRFWGTKTY QIEGLTGAET NQTDPPVKHS
KPGEQCVAAA GTHGFTVTDT RVIKDLGGRE IKRESRSVRY DGQPKIVCTP QDDHKPNG
//
