ID A0A1M4UW30_9FLAO Unreviewed; 531 AA.
AC A0A1M4UW30;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=SAMN05444278_103131 {ECO:0000313|EMBL:SHE60981.1};
OS Psychroflexus salarius.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Psychroflexus.
OX NCBI_TaxID=1155689 {ECO:0000313|EMBL:SHE60981.1, ECO:0000313|Proteomes:UP000184462};
RN [1] {ECO:0000313|EMBL:SHE60981.1, ECO:0000313|Proteomes:UP000184462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25661 {ECO:0000313|EMBL:SHE60981.1,
RC ECO:0000313|Proteomes:UP000184462};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; FQTW01000003; SHE60981.1; -; Genomic_DNA.
DR RefSeq; WP_073192581.1; NZ_FQTW01000003.1.
DR AlphaFoldDB; A0A1M4UW30; -.
DR STRING; 1155689.SAMN05444278_103131; -.
DR OrthoDB; 9767858at2; -.
DR Proteomes; UP000184462; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:SHE60981.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000184462}.
FT DOMAIN 303..435
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 531 AA; 61852 MW; E92D2CE1B6285BA6 CRC64;
MKLFAELVKT IDSTNKTNAK VEALAHYFKT APDQDKVWTI AILSHRRPKR PINSTLIREY
ASKLANIPLW LFEESYHIVG DLAETIALVV PSSSNNSDKT LTQFINEIIA LKSSSETKKK
DYLITNWQNL NYYERFVFTK LITGGFRIGV SQKLMTRALS KATEIDEETL AFKLMGNWKP
TELSFQELIL EPNPKADLSK PYPFYLAYPV EDDVVNTKNV SQFYFEHKWD GIRAQIICRQ
NECFVWSRGE ELVTHQFPEF KRFAEILPDD TVLDGEILAF PNQSIGDFKD LQQRINRKTV
SKKMLQKIPV IFKAYDLLEF NNQDIRSQSY QERRRLLDHL YITYHSEIKA FHLSHLMQFK
SWQDAVNERE TAREKKSEGL MIKRSASSYG VGRKKGDWYK WKSDPFTIDA VLTYAMRGHG
RRSNLFTDYT FALWDNNHEN LVTFAKAYSG LTDAEFKEID KWIKANTLER FGPVRSVKPH
HVFEIAFEGI ATSKRHKSGV ATRFPRIVRW RKDKPTTEAN TLEELKALIP K
//
