ID A0A1M4VCJ8_9ACTN Unreviewed; 713 AA.
AC A0A1M4VCJ8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SHE66578.1};
GN ORFNames=SAMN02745225_01275 {ECO:0000313|EMBL:SHE66578.1};
OS Ferrithrix thermotolerans DSM 19514.
OC Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC Acidimicrobiaceae; Ferrithrix.
OX NCBI_TaxID=1121881 {ECO:0000313|EMBL:SHE66578.1, ECO:0000313|Proteomes:UP000184295};
RN [1] {ECO:0000313|Proteomes:UP000184295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19514 {ECO:0000313|Proteomes:UP000184295};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQUL01000015; SHE66578.1; -; Genomic_DNA.
DR RefSeq; WP_072790115.1; NZ_FQUL01000015.1.
DR AlphaFoldDB; A0A1M4VCJ8; -.
DR STRING; 1121881.SAMN02745225_01275; -.
DR GeneID; 78385984; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000184295; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF01443; Viral_helicase1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000184295}.
FT DOMAIN 187..566
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT COILED 14..41
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 208..215
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 713 AA; 80914 MW; 13576793C0F86E4D CRC64;
MASQKDLEFE SGYVKMAYKR LEEIKQQIKS SMNQVLEVER GGTHQAKVER DVVVRSSLAR
LENLEIGDQA LIFGRIDFQP PAELSEGESY HIGRVSVNSE TMEPLVVDWR APIAEAFYRA
TGKDTMGVKL RRHIFCNRDV VVNIEDEWLS SLEEDSREGY LEPPSPSALF SAISKPRTSY
MSDIVSTIQA EQDEIVRYPL SGILVVQGAP GTGKTAVALH RAAYLMYTHR WRFERQPLLV
IGPSSEFVKY ISRVLPSLGE SGVELHTIAG LCGFAEAAFE PEIQRRRLKG DLRMEKLLRK
AVRDRERPLR KDLRLAFGRK YLTVTTEMSQ ELVRSMKRRP GPHNPKRKVI ELRLSQLLAE
QYLEGGDLTT EVRAVTNVIS IHAGLEDQVA QHLPGEDGVE VAREVAAALR KSVEFQLVVE
RIWPRLSAEE TLYDLFSHRA LLKLAAKDIL SEEELDVLTI DQGVDVKRHQ WSIEDVVLLD
ELQTFLDEQS DDDVTFGHVI VDEAQDISPM TARLLKRKCP SGSMTILGDL AQSFGPWPNR
RWDDILEPLS SKDHHMLELS VNYRTSQEIS ELADLIKSRY LAGSRRTKSI RSFPGGVQFI
EAKDLIQRAV ADAKDLFERK EQGRFAMIVP NKDSEALRRE IDKEGLSEWE SISVIGVEQV
RGLEFDEVFI LEPLSLVDDA ERSLPALYVA VTRATNRIKI YSSQPFPNWL LVK
//
