ID A0A1M4VYI6_9THEO Unreviewed; 314 AA.
AC A0A1M4VYI6;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SHE74071.1};
GN ORFNames=SAMN02746089_00705 {ECO:0000313|EMBL:SHE74071.1};
OS Caldanaerobius fijiensis DSM 17918.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Caldanaerobius.
OX NCBI_TaxID=1121256 {ECO:0000313|EMBL:SHE74071.1, ECO:0000313|Proteomes:UP000184088};
RN [1] {ECO:0000313|EMBL:SHE74071.1, ECO:0000313|Proteomes:UP000184088}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17918 {ECO:0000313|EMBL:SHE74071.1,
RC ECO:0000313|Proteomes:UP000184088};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FQVH01000005; SHE74071.1; -; Genomic_DNA.
DR RefSeq; WP_073341817.1; NZ_FQVH01000005.1.
DR AlphaFoldDB; A0A1M4VYI6; -.
DR STRING; 1121256.SAMN02746089_00705; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000184088; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000184088}.
FT DOMAIN 12..308
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 104..277
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 314 AA; 35098 MW; 2FA6B5F4B39AB6A9 CRC64;
MKKILFFKKR NISEGLMKKI KEAAAGYDVI VENNLKSALK LVKDVEIIAG EVENDLIKAG
NALKWVHVWS AGVDNYDLAY MKDKGIILTN SSGVHSIQIS EYILGVMLEL TKGLHLLRDQ
QARKLWGKVS TDELYKKTLG VLGVGDIGRR TAELGKAMGM RVLGYRKSGR PDEYVDVMYS
EGQLDDMLPL CDFVVNTLPL TDSTYHLIGA AQFNAMKDGA YFINIGRGKV VDENALINAL
RSNKLKGAAL DVFEEEPLPQ ESPLWDMENV IITPHISGLS PSYDERAISI LVENIERYIQ
GRPMLNQVDF DRGY
//
