ID A0A1M4W8Q3_9CLOT Unreviewed; 573 AA.
AC A0A1M4W8Q3;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ferredoxin hydrogenase {ECO:0000313|EMBL:SHE77535.1};
GN ORFNames=SAMN05443638_1118 {ECO:0000313|EMBL:SHE77535.1};
OS Clostridium fallax.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1533 {ECO:0000313|EMBL:SHE77535.1, ECO:0000313|Proteomes:UP000184035};
RN [1] {ECO:0000313|EMBL:SHE77535.1, ECO:0000313|Proteomes:UP000184035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2631 {ECO:0000313|EMBL:SHE77535.1,
RC ECO:0000313|Proteomes:UP000184035};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FQVM01000011; SHE77535.1; -; Genomic_DNA.
DR RefSeq; WP_072895437.1; NZ_UAVV01000002.1.
DR AlphaFoldDB; A0A1M4W8Q3; -.
DR STRING; 1533.SAMN05443638_1118; -.
DR OrthoDB; 9805142at2; -.
DR Proteomes; UP000184035; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR NCBIfam; NF040762; Hydr_FeFe_Clost; 1.
DR PANTHER; PTHR11615:SF6; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000184035}.
FT DOMAIN 2..78
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 78..117
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 138..167
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 181..210
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 573 AA; 64510 MW; 55D8A06E7E0A9FEE CRC64;
MKKVIINGVL IEESKDITIL ELAKANKIDI PNLCFLKDCN GGNNCGICGV EVEGEKNLIT
ACNTIIKDGM VINTKSERVL ENAKEKVSKL LDTHEFKCGP CKRRENCEFL KIVIKTKGRA
SKPFIVENKK DYIDDRSKSL VIDRSKCVKC GRCVAACKAK TGTESIEFYK KDDVKIIRPK
NGISFDEGKC LLCGQCVMAC PVDALYEKSH IERVKEALED PKKHVLVAIA PSVRTAMGEL
FGMGYGVDVT GKLYSALRLL GFDKIFDINF GADMTIMEET TELLERIKNN GPFPMFTSCC
PAWVRQVENY YPNYLENLST AKSPQQIFGT ATKTYYPHIE DIDPKNVFTV TIMPCTAKKF
EADREEMKYK EYRDIDAVIT TRELARFIKE KKIDFKNLED SECDPAMGEY TGAGAIFGAT
GGVMEAALRT AKDFIENQDL SNIEYKMVRG LKGIKEAKVI LNNKEYNIAV VNGAKNLKEF
MDSDNLNKKQ YHFIEVMACE GGCVNGGGQP HISSSERENI NIREVRASVL YNQDRNLKKR
KSHENTALIK MYKTYFGEAG KGKAHELLHH KYK
//
