ID A0A1M4XQE1_9BACT Unreviewed; 948 AA.
AC A0A1M4XQE1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05443144_104186 {ECO:0000313|EMBL:SHE95665.1};
OS Fodinibius roseus.
OC Bacteria; Balneolota; Balneolia; Balneolales; Balneolaceae; Fodinibius.
OX NCBI_TaxID=1194090 {ECO:0000313|EMBL:SHE95665.1, ECO:0000313|Proteomes:UP000184041};
RN [1] {ECO:0000313|EMBL:SHE95665.1, ECO:0000313|Proteomes:UP000184041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21986 {ECO:0000313|EMBL:SHE95665.1,
RC ECO:0000313|Proteomes:UP000184041};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FQUS01000004; SHE95665.1; -; Genomic_DNA.
DR RefSeq; WP_073060567.1; NZ_FQUS01000004.1.
DR AlphaFoldDB; A0A1M4XQE1; -.
DR STRING; 1194090.SAMN05443144_104186; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000184041; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd03270; ABC_UvrA_I; 1.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 592..935
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 948 AA; 106371 MW; DC658E9D1F901A6A CRC64;
MRENIVIRGA REHNLKNIDV NIPREKLVVV TGISGSGKSS LAFDTIYAEG QRRFLESLSA
YARQFLGMME RPEVDFIDGL SPVISIDQKT TNRNPRSTVG TVTEIYDFLR LLYARIGVPY
SWKTGNRMSK QTSEEVVSAI MDMPEGTKAY CLAPVVRGRK GHYRELFEQT MKQGFVQVRV
DGELMDIEEG MKVDRYKTHN IEVVVDRFVI NRNSEKRIAE SVRLALEMAE GNVILSVPNE
EVGFDDHLYS QNLFDPESGL AYEDPAPNMF SFNSPYGACQ NCDGLGYTYD VDRNLVIPNK
EQTIEEGAIR FLGKPRDIFA FKQLKAVLKT LDLDFETPID EFSEEALDLL FEGGGDRKYD
VSYDFRRDNV TYKHSFDGLR NMIREQYKES KSNKKRDKAK AYMSKIACPD CGGGRLNKES
LSYKIDGYSI DDLVQLDIKT LRHTLNNLDL DERQQKIGSQ VLKEVRDRVD FLLNVGLNYL
TLDREAQTLS GGEAQRIRLA TQIGTQLVGV LYILDEPSIG LHQRDNIKLI RSLETLRDLG
NSVIVVEHDR ETIEQADYVL DLGPGAGEHG GEIVTEGRPD ELDPDSMTAR FLNDEEAVPY
SEERREGSGQ LVRLEGARGH NLKQVDVDIP LGKFICVTGV SGSGKSSLVN QTLEPILSTE
FYNSKSVPLP YDEVHGIDNL DKIISVDQSP IGRTPRSNPG TYTKVFDHIR KLFAQLPESK
IRGYDQGRFS FNVKGGRCEA CNGDGVRKIE MNFLPDVYVD CETCNGKRYN RETLEIYYKG
KNISDVLNMS IREAHDFFDS VPAINRILGT LVDVGLGYLR LGQPSTTLSG GEAQRIKLAR
ELAKVGTGDT LYIMDEPTTG LHFQDVRLLV DVAQQLVDKG NTVIVIEHNL DLIKAADWII
DLGPEGGQEG GEIIAEGTPE EVAEAEGSAT GTFLKEEFER EKNQRITA
//
