ID   A0A1M4XXA0_9FIRM        Unreviewed;       230 AA.
AC   A0A1M4XXA0;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases {ECO:0000313|EMBL:SHE98089.1};
GN   ORFNames=SAMN02746064_01617 {ECO:0000313|EMBL:SHE98089.1};
OS   Alkalibacter saccharofermentans DSM 14828.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Alkalibacter.
OX   NCBI_TaxID=1120975 {ECO:0000313|EMBL:SHE98089.1, ECO:0000313|Proteomes:UP000184251};
RN   [1] {ECO:0000313|EMBL:SHE98089.1, ECO:0000313|Proteomes:UP000184251}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14828 {ECO:0000313|EMBL:SHE98089.1,
RC   ECO:0000313|Proteomes:UP000184251};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FQTU01000011; SHE98089.1; -; Genomic_DNA.
DR   RefSeq; WP_073270896.1; NZ_FQTU01000011.1.
DR   AlphaFoldDB; A0A1M4XXA0; -.
DR   STRING; 1120975.SAMN02746064_01617; -.
DR   OrthoDB; 3176638at2; -.
DR   Proteomes; UP000184251; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   PANTHER; PTHR24567:SF58; CYCLIC AMP-BINDING REGULATORY PROTEIN; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SMART; SM00419; HTH_CRP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:SHE98089.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184251};
KW   Transferase {ECO:0000313|EMBL:SHE98089.1}.
FT   DOMAIN          14..116
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          155..223
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51063"
SQ   SEQUENCE   230 AA;  26308 MW;  B5D7B3DC0DB05BD5 CRC64;
     MLKKYYKILE KNPLFDNIDD YSIDQLLGCL QPKVKTYEKN EFIAFAGDEF TSIGVVLEGQ
     VTVIKENASG NKVMMSLLDP GDMFGEMIAF SNFSKWPATV QATKNATIMF MEKSAIVGDC
     PKMCTWHKSL IQNMLKIVSN RALMLNKKVE YLSIKSMRGK LSNFFLEEYK KSKGQVLDLS
     MNRNELADFL NVSRPSMSRE MGKLKEEGII DYKKNQIRII DFDGLKEMAE
//