ID   A0A1M4Y2Z2_9BACT        Unreviewed;       257 AA.
AC   A0A1M4Y2Z2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:SHF00058.1};
GN   ORFNames=SAMN05444362_10357 {ECO:0000313|EMBL:SHF00058.1};
OS   Dysgonomonas macrotermitis.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae;
OC   Dysgonomonas.
OX   NCBI_TaxID=1346286 {ECO:0000313|EMBL:SHF00058.1, ECO:0000313|Proteomes:UP000184480};
RN   [1] {ECO:0000313|Proteomes:UP000184480}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 27370 {ECO:0000313|Proteomes:UP000184480};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FQUC01000003; SHF00058.1; -; Genomic_DNA.
DR   RefSeq; WP_062177221.1; NZ_FQUC01000003.1.
DR   AlphaFoldDB; A0A1M4Y2Z2; -.
DR   STRING; 1346286.SAMN05444362_10357; -.
DR   OrthoDB; 1522519at2; -.
DR   Proteomes; UP000184480; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184480}.
FT   DOMAIN          1..257
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   257 AA;  29046 MW;  87C01BFB56EDB5D9 CRC64;
     MKILILGAGK MGSFFSDVLS SDHEVALFDT DPNRLKFTYN VIRLSDPNEI RTFDPELVIN
     AVTVKYTIEA FKSILPYISD TCIVSDIASV KTGLQDFYAS LKQPFASSHP MFGPTFADLR
     NLTTQSAIVI SESSEIGKKF FLDLYRSLSL QVFEYTFDEH DETIAYSLSI PFASTLVFAS
     VMKHQEAPGT TFKRHMDIAK GLLSEDDYLL TEVLFNPYTP NQVEQIRAEL AHLLTIIEKK
     DTPAMKEFLT KVRKNIE
//