ID A0A1M4Z1S7_9FIRM Unreviewed; 890 AA.
AC A0A1M4Z1S7;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SHF12011.1};
GN ORFNames=SAMN02746064_01918 {ECO:0000313|EMBL:SHF12011.1};
OS Alkalibacter saccharofermentans DSM 14828.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Alkalibacter.
OX NCBI_TaxID=1120975 {ECO:0000313|EMBL:SHF12011.1, ECO:0000313|Proteomes:UP000184251};
RN [1] {ECO:0000313|EMBL:SHF12011.1, ECO:0000313|Proteomes:UP000184251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14828 {ECO:0000313|EMBL:SHF12011.1,
RC ECO:0000313|Proteomes:UP000184251};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FQTU01000015; SHF12011.1; -; Genomic_DNA.
DR RefSeq; WP_073271426.1; NZ_FQTU01000015.1.
DR AlphaFoldDB; A0A1M4Z1S7; -.
DR STRING; 1120975.SAMN02746064_01918; -.
DR OrthoDB; 9804747at2; -.
DR Proteomes; UP000184251; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000184251};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 356..408
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 424..497
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 502..554
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 583..713
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 704..890
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 890 AA; 100921 MW; 976FE2D1313A2D38 CRC64;
MKAKSISIKT VIILVFLIAL LILTGGSLYI VFDNWMKSAE DTTATLADEL HREIITEVNE
YMHVPRHIVE VNRGLIERKI VEIDNSAERD VFFINSMKTH IDEEVYSFSF GTNAGEYYGA
RKNQLNEIEV MINNSETNGE SWYYSIDEQH RLVKKVVNAG SFDPRTRDWF KAAIDSEEVV
FSPVYKHFVM HDLTVSAAVP IYDDSGELYG VLSSHMTLNR INENLEEISR GNKALIAIVE
RDTGYVIANS IGTDNFMENS DGIFERITVE DLDDKALSGI YNNYINMDEY EKLDVEGDAY
QSRISPYQAN GIDWLVISTV PLSLITNDLF LGMQKALAYS LSISTALFLI FVFGVKRLLS
PIDELVRVNE KLIKGDLTAR AGPSKYIEVG RLADSFNETA DELYHLIYNL ESEVEMRTYE
LFNEKERFRT TLLSVGDGVI ATDKKGLVTV MNPIAENLTG WSLSEAKGKH FIDVFKIINE
QTREICEDPV QKVLDTGGIV ELANHTVLIA KNGRETPIED SVGPIKAQSG KITGVVIVFR
DFSDKKEKLK EIEYLSFHDH LTGLYNRRYM EDTIARLDQD RNLPLAIMVI DVNGLKLTND
AFGHKMGDEL LVRVSNILKE KCRSVDIVGR MGGDEFCVLL PKTSLEEAEQ VKKRILNRAS
NTKIDSIVVS LAVGFAVKEN KGQDIKDVMT IADNNMYKDK LKYGKAMRNR TIETVLKNIN
HKYDQEQIHT ERVSQYCEEI ARAMGFEENK IQEIKTAGIL HDIGKIMVPS EILNKPSKLT
DEEFEIIKRH PETSYQILKS VDEYSVFAED VLYHHERPDG KGYPEGLIGD EIPINSRIIA
VADAYEAMTA KRPYQNPKSK DEALEELVRC SGTQFDLKIV DIFVNIMRKA
//
