ID A0A1M4ZYF9_9FIRM Unreviewed; 332 AA.
AC A0A1M4ZYF9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:SHF23090.1};
GN ORFNames=SAMN02746064_02179 {ECO:0000313|EMBL:SHF23090.1};
OS Alkalibacter saccharofermentans DSM 14828.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Alkalibacter.
OX NCBI_TaxID=1120975 {ECO:0000313|EMBL:SHF23090.1, ECO:0000313|Proteomes:UP000184251};
RN [1] {ECO:0000313|EMBL:SHF23090.1, ECO:0000313|Proteomes:UP000184251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14828 {ECO:0000313|EMBL:SHF23090.1,
RC ECO:0000313|Proteomes:UP000184251};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|ARBA:ARBA00001968};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the PdxA family. PdxA2 subfamily.
CC {ECO:0000256|ARBA:ARBA00009464}.
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DR EMBL; FQTU01000021; SHF23090.1; -; Genomic_DNA.
DR RefSeq; WP_073272077.1; NZ_FQTU01000021.1.
DR AlphaFoldDB; A0A1M4ZYF9; -.
DR STRING; 1120975.SAMN02746064_02179; -.
DR OrthoDB; 9801783at2; -.
DR Proteomes; UP000184251; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR005255; PdxA_fam.
DR NCBIfam; TIGR00557; pdxA; 1.
DR PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR Pfam; PF04166; PdxA; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000184251}.
SQ SEQUENCE 332 AA; 36357 MW; B99C0F3B0B13C72B CRC64;
MKRAVVGIPM GDPAGVGPEI IVKALTVKEI HQNSKVVVIG DKETIKQAME ICNIDLQINV
IQDVEEGEYK AGILNLIDLN NVDIEKLEFG KVQAMAGRAA FDYIKHSVEL ASAGKIDVLA
TTPINKEALK AGEINYIGHT EMLADLTNTH DPLTMFEVFN LRVFFLSRHV SLKKACDMVT
KERVLEYIER CHVALERLGI KGGKLAIAGL NPHSGEHGLF GREEVDEIQP AIEEAQKRGF
NVVGPVPADS VFHFGLKGSY DAVLSLYHDQ GHIATKMVDF ERTISLTNNM PFLRTSVDHG
TAFDIAGTGK VSAASMIEAI KVAAKYGPHF RK
//
