ID A0A1M5A351_9GAMM Unreviewed; 339 AA.
AC A0A1M5A351;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=L-threonine aldolase {ECO:0000313|EMBL:SHF24701.1};
GN ORFNames=SAMN02745204_02101 {ECO:0000313|EMBL:SHF24701.1};
OS Thermomonas hydrothermalis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Thermomonas.
OX NCBI_TaxID=213588 {ECO:0000313|EMBL:SHF24701.1, ECO:0000313|Proteomes:UP000242857};
RN [1] {ECO:0000313|Proteomes:UP000242857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14834 {ECO:0000313|Proteomes:UP000242857};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; FQUK01000046; SHF24701.1; -; Genomic_DNA.
DR RefSeq; WP_072756505.1; NZ_FQUK01000046.1.
DR AlphaFoldDB; A0A1M5A351; -.
DR STRING; 213588.SAMN02745204_02101; -.
DR OrthoDB; 9774495at2; -.
DR Proteomes; UP000242857; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd06502; TA_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000242857}.
FT DOMAIN 5..285
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 199
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 339 AA; 36470 MW; 87A2C9182E471C41 CRC64;
MHVVDLRSDT VTQPTAAMRE AMQAAPVGDD VYGEDPTVNA LQERLAAMLG FEAGLFVPTG
TQSNLLALLS HCERGDEYLV GMDAHTYKFE GGGAAVLGSI QPQPIVQAED GSLPLDRVAA
AIKPVDPHFA RTRLLALENT WHGRTLPLDY LRAAGDLARE RGLGYHLDGA RLFNAAVACG
VPAREIARHF DTVSVCLSKG LGAPVGSVLV GSRALIDKAR RWRKVCGGGW RQAGMLAAAG
LYALDHHIDR LADDHARAAR LAERLRAIDG LTVLGQHTNM VFIDVPVARL RDLDAHLRAA
GIRISIGYLP TVRLVTHLDI DDEGIERTAD AFARFFAAG
//
