ID A0A1M5D6D8_9FLAO Unreviewed; 275 AA.
AC A0A1M5D6D8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=protein acetyllysine N-acetyltransferase {ECO:0000256|ARBA:ARBA00012928};
DE EC=2.3.1.286 {ECO:0000256|ARBA:ARBA00012928};
GN ORFNames=SAMN05443633_105166 {ECO:0000313|EMBL:SHF62435.1};
OS Chryseobacterium arachidis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1416778 {ECO:0000313|EMBL:SHF62435.1, ECO:0000313|Proteomes:UP000184518};
RN [1] {ECO:0000313|EMBL:SHF62435.1, ECO:0000313|Proteomes:UP000184518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27619 {ECO:0000313|EMBL:SHF62435.1,
RC ECO:0000313|Proteomes:UP000184518};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FQUT01000005; SHF62435.1; -; Genomic_DNA.
DR RefSeq; WP_072957644.1; NZ_FQUT01000005.1.
DR AlphaFoldDB; A0A1M5D6D8; -.
DR STRING; 1416778.SAMN05443633_105166; -.
DR OrthoDB; 9800582at2; -.
DR Proteomes; UP000184518; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1600.10; SIR2/SIRT2 'Small Domain; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR003000; Sirtuin.
DR InterPro; IPR026591; Sirtuin_cat_small_dom_sf.
DR InterPro; IPR026590; Ssirtuin_cat_dom.
DR PANTHER; PTHR11085:SF12; NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11085; NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02146; SIR2; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR PROSITE; PS50305; SIRTUIN; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00236};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00236}.
FT DOMAIN 1..275
FT /note="Deacetylase sirtuin-type"
FT /evidence="ECO:0000259|PROSITE:PS50305"
FT ACT_SITE 125
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT BINDING 133
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT BINDING 137
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT BINDING 166
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT BINDING 169
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
SQ SEQUENCE 275 AA; 31989 MW; 2C439EA9C370D78B CRC64;
MEELQLILKT ILKEKQGYIT FLTGAGISAE SGLPTYRSID GIWIKGTKYH KPEEFGTYKY
FSQNQEEVWQ YNLFWKKMIA EAKPNLGHFA ITEIEKLLGD RFKLITQNVD GLHQRSGTQK
VYEIHGSKQK VRCSKECSEP FDFPENIKYK EYMEDLTPDD IDDLKCKKCG NWLRPHTLWF
DESYNEKYYH FDTAYHIADH TDILFVIGTS GSTALPVNIV ETVKIRAKWI VLINPENDTY
FDYILKGSKT LHSIQESSSV ALPQLKNMME EMINS
//
