ID A0A1M5EH60_9BACT Unreviewed; 488 AA.
AC A0A1M5EH60;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Leucyl aminopeptidase {ECO:0000313|EMBL:SHF78500.1};
GN ORFNames=SAMN05720760_101642 {ECO:0000313|EMBL:SHF78500.1};
OS Fibrobacter sp. UWB8.
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=1896207 {ECO:0000313|EMBL:SHF78500.1, ECO:0000313|Proteomes:UP000184492};
RN [1] {ECO:0000313|Proteomes:UP000184492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UWB8 {ECO:0000313|Proteomes:UP000184492};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
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DR EMBL; FQVZ01000001; SHF78500.1; -; Genomic_DNA.
DR RefSeq; WP_073054209.1; NZ_FQVZ01000001.1.
DR AlphaFoldDB; A0A1M5EH60; -.
DR Proteomes; UP000184492; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00433; Peptidase_M17; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR000819; Peptidase_M17_C.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW ECO:0000313|EMBL:SHF78500.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT DOMAIN 334..341
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
SQ SEQUENCE 488 AA; 53268 MW; 8FE5D7432E3B67C5 CRC64;
MNLNIVSSEN LKNVDSKAYA LFYVKESVQF STVLSPEGEE QVETILKGMK EGPFEDLEYL
EIDGCNTFFV DAAKERGLSA LDHLRMAAYR LAKKAMKKQI PCVSLFLADA ADEQFKAILH
GLHYADYKFD AYKSKQKPNF QVTYEIVAGE HVKEFKKIAE DVAVEQKAIT LAKNLINTSA
SDLYPAKFVE RAKTVAKYTE GLSIKVRNMK QLEKEGFMGH VTVGKGSSHE PHMITLEYKP
SKRTSKDHLV IVGKGLTFDT GGLCLKPPKS MPEMISDMSG AATALAAIQA IATLKLPIRV
SAVCCLAENA IGNKSVLPGD IFTAKNGKTV MVDNTDAEGR LVLSDGLAEA GLIGATHIVD
LATLTGAMVR ALGYAVTGFF SNDDDLGLKV INCGEACCEK FWSMPLEEEY ADALKDHFAD
LKNTGSDAGA ISAALFLQEF VPENTAWTHW DIAGTAFVDK KWKYTEYGAT GFGVQTLIQL
AREFSAAE
//
