ID A0A1M5EVQ5_9BACT Unreviewed; 320 AA.
AC A0A1M5EVQ5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Diacylglycerol kinase eta {ECO:0000256|ARBA:ARBA00017201};
DE EC=2.7.1.107 {ECO:0000256|ARBA:ARBA00012133};
GN ORFNames=SAMN05720760_101820 {ECO:0000313|EMBL:SHF83304.1};
OS Fibrobacter sp. UWB8.
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=1896207 {ECO:0000313|EMBL:SHF83304.1, ECO:0000313|Proteomes:UP000184492};
RN [1] {ECO:0000313|Proteomes:UP000184492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UWB8 {ECO:0000313|Proteomes:UP000184492};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Phosphorylates diacylglycerol (DAG) to generate phosphatidic
CC acid (PA). {ECO:0000256|ARBA:ARBA00002064}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase family.
CC {ECO:0000256|ARBA:ARBA00009280}.
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DR EMBL; FQVZ01000001; SHF83304.1; -; Genomic_DNA.
DR RefSeq; WP_073054495.1; NZ_FQVZ01000001.1.
DR AlphaFoldDB; A0A1M5EVQ5; -.
DR Proteomes; UP000184492; Unassembled WGS sequence.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF34; DIACYLGLYCEROL KINASE ETA; 1.
DR Pfam; PF00609; DAGK_acc; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00045; DAGKa; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SHF83304.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..139
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 320 AA; 35473 MW; 36129E511A7707CD CRC64;
MYKFVFLINP ISGGGQGKVI HQYLPEIMSS LNYTEDQWKA EFTNIDGLDN QIRDALANTE
KLVAVGGDGT VSSVLSVMVS SEYAKSVKIG LIPLGTGNDL ARVLNLYKPY VDKGLLFLVR
RLLQAKARPF DIWKVNGKLA FANYFSGGID ARIAHDFNRA RANGEFNSNS VLVNKLHYVK
SFFADRSYQL KKGKLSFVDA EGRSWQKILD GHRTVIVGNI PSFASGTNPF YKSDMADGLL
EIVCVPNMFR FLLAIAVGNL PVIGNLVKKY FIKTRKARSL KLEFAEDEFL QLDGEDLSGK
LGGHVDIDFA CKVQIMALGE
//
