ID A0A1M5F308_9FLAO Unreviewed; 452 AA.
AC A0A1M5F308;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cystathionine beta-synthase {ECO:0000313|EMBL:SHF85885.1};
GN ORFNames=SAMN05444344_1732 {ECO:0000313|EMBL:SHF85885.1};
OS Tenacibaculum mesophilum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Tenacibaculum.
OX NCBI_TaxID=104268 {ECO:0000313|EMBL:SHF85885.1, ECO:0000313|Proteomes:UP000183998};
RN [1] {ECO:0000313|EMBL:SHF85885.1, ECO:0000313|Proteomes:UP000183998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13764 {ECO:0000313|EMBL:SHF85885.1,
RC ECO:0000313|Proteomes:UP000183998};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; FQVV01000002; SHF85885.1; -; Genomic_DNA.
DR RefSeq; WP_073182975.1; NZ_FQVV01000002.1.
DR AlphaFoldDB; A0A1M5F308; -.
DR STRING; 104268.SAMN05444344_1732; -.
DR OrthoDB; 9808024at2; -.
DR Proteomes; UP000183998; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:UniProt.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR001216; P-phosphate_BS.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS00901; CYS_SYNTHASE; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 340..397
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 452 AA; 50224 MW; C3D09D7164DB5481 CRC64;
MKYAKNILET IGNTPLVQLN SVTKEVDALV LAKVETFNPG NSVKDRMALK MIEDAEADGR
LKPGGTIIEG TSGNTGMGLA LAAIVKGYKC IFVISDKQSK EKMDILRAVG AEVVVCPTNV
EPDDPRSYYS VSKRLGEETP NSWYVNQYDN PSNAQAHYEQ TGPEIWEQTD GKITHFVVGV
GTGGTVSGTA KFLKEKNPNI KIWGVDTYGS VFKKYHETGI FDENEIYPYI TEGIGEDILP
KNVDFSLIDG FTKVTDKDAA IYTRKIAKEE GIFVGNSAGS AIKGLLQLKD EFKPDDVVVV
LFHDHGSRYV GKMFNDDWMR DRGFLDEEIT TAEDLIKDHI DKPLVTVQTE ELVSHAIERM
RAFKISQIPV RDVNGFVGSV DESALLYSYL EDKNIAEKPI KDVMGRTYPT VKKSASIDEV
SKLINKENQA VLVDLENGKH HIITKYDIIR AI
//
