ID A0A1M5FLE5_9RHOB Unreviewed; 548 AA.
AC A0A1M5FLE5;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=SAMN05444339_1229 {ECO:0000313|EMBL:SHF92249.1};
OS Loktanella atrilutea.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Loktanella.
OX NCBI_TaxID=366533 {ECO:0000313|EMBL:SHF92249.1, ECO:0000313|Proteomes:UP000183987};
RN [1] {ECO:0000313|Proteomes:UP000183987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 29326 {ECO:0000313|Proteomes:UP000183987};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; FQUE01000022; SHF92249.1; -; Genomic_DNA.
DR RefSeq; WP_072858927.1; NZ_FQUE01000022.1.
DR AlphaFoldDB; A0A1M5FLE5; -.
DR STRING; 366533.SAMN05444339_1229; -.
DR OrthoDB; 9806213at2; -.
DR Proteomes; UP000183987; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR011639; MethylTrfase_TaqI-like_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF07669; Eco57I; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SHF92249.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000183987};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHF92249.1}.
FT DOMAIN 204..303
FT /note="Type II methyltransferase M.TaqI-like"
FT /evidence="ECO:0000259|Pfam:PF07669"
SQ SEQUENCE 548 AA; 61420 MW; 0EFA80F83FBB4203 CRC64;
MSVAPFTLRG RNPDVLSCIA NLSNDEVFTP PEFANRMLDT LAEAWAADHD GASLWVNPDV
TFLDPCTKSG VFLREIAKRL IDGLEGHIPD RQARLDHILT RQVFGIGITE LTAMLARRSL
YCSKHANGKH SITRGFNSKS GNVWFERVEH TWEKPDEKNK GKCVFCGASS SILDRGDDRE
SHAYTFIHTD NIQARASALF GGNMHFDVII GNPPYQLDDG GHGTSAAPIY HKFVEQAKAL
DPRYLTMVIP SRWFAGGKGL DEFRQSMLSD NRLRSITDYL SAADVFPGVG LKGGVCYFLW
DRDHPGACQI LTNFKDWPVS EATRPLLETG AEIFIRFNEG VSILKKVMGV ETGQADNLSL
SEDRRFETLV SSRKPFGFTT NFKGRKTKKV NDLLIYQNGG TGFVSREQVE GGVHLIDKWK
LFAGYAAPGT GNRDTYPHRI ISTPFIAGPG TVSSETYLSM GPFDTEAQAK SALSYISCRL
TRFMVLLHKS SQHVTRKVYT FVPKQTWDRQ WTDQVLYEKY GLTEDEIAFV EKIVRPMDMD
LFDNPAEL
//
