ID A0A1M5GA10_9BACI Unreviewed; 400 AA.
AC A0A1M5GA10;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=3-oxo-5,6-didehydrosuberyl-CoA/3-oxoadipyl-CoA thiolase {ECO:0000313|EMBL:SHG00585.1};
GN ORFNames=SAMN05216225_101222 {ECO:0000313|EMBL:SHG00585.1};
OS Ornithinibacillus halophilus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Ornithinibacillus.
OX NCBI_TaxID=930117 {ECO:0000313|EMBL:SHG00585.1, ECO:0000313|Proteomes:UP000183988};
RN [1] {ECO:0000313|EMBL:SHG00585.1, ECO:0000313|Proteomes:UP000183988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBRC-M 10683 {ECO:0000313|EMBL:SHG00585.1,
RC ECO:0000313|Proteomes:UP000183988};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FQVW01000012; SHG00585.1; -; Genomic_DNA.
DR RefSeq; WP_072889477.1; NZ_FQVW01000012.1.
DR AlphaFoldDB; A0A1M5GA10; -.
DR STRING; 930117.SAMN05216225_101222; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000183988; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF2; 3-OXOADIPYL-COA_3-OXO-5,6-DEHYDROSUBERYL-COA THIOLASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000183988};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 4..269
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 276..397
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 355
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 385
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 400 AA; 43114 MW; AA0F1430308DDB7D CRC64;
MREVVIVDAV RTPIGRYKGA LKSIRPDDLA AIVIEALLKR NENLPPEEIE EVVLGNANQA
GEDNRNVARM SALLAGLPVT VSGTTINRLC GSGLDAVMYA ARAIAVGEGD IFIAGGTESM
TRAPYVMPKP EKDFPRGNME MYDTTIGWRF INKKLEGMYG TDSMPQTAEN VAEMYGISRI
EQDQFALESQ HRAKQAVASN RFSEELVPVI YHDRKGKKSV VDHDEHPRPE TTIEKLGKLR
PLFEEGTITA GNASGVNDGA SALLIMSKEK AEKLGLKPLV KYVVGATAGL EPRVMGLGPI
HATQKAVARA GLTMDHIGLV ELNEAFASQS LACMRQLELD HSKVNVNGGA IAFGHPLGAS
GARILTTLIH EMKKRDTKYG LATMCVGVGQ GISAIVENVD
//
