ID A0A1M5GIX1_9FLAO Unreviewed; 295 AA.
AC A0A1M5GIX1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Conserved TM helix {ECO:0000313|EMBL:SHG03643.1};
GN ORFNames=SAMN05444344_2485 {ECO:0000313|EMBL:SHG03643.1};
OS Tenacibaculum mesophilum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Tenacibaculum.
OX NCBI_TaxID=104268 {ECO:0000313|EMBL:SHG03643.1, ECO:0000313|Proteomes:UP000183998};
RN [1] {ECO:0000313|EMBL:SHG03643.1, ECO:0000313|Proteomes:UP000183998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13764 {ECO:0000313|EMBL:SHG03643.1,
RC ECO:0000313|Proteomes:UP000183998};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; FQVV01000004; SHG03643.1; -; Genomic_DNA.
DR RefSeq; WP_073184113.1; NZ_FQVV01000004.1.
DR AlphaFoldDB; A0A1M5GIX1; -.
DR OrthoDB; 1522493at2; -.
DR Proteomes; UP000183998; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR008910; MSC_TM_helix.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF05552; MS_channel_1st_1; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..178
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 187..273
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 295 AA; 32624 MW; A0C3849D5D62B276 CRC64;
MNFSSTIAKL KESVQLYWNE FINQIPKIII AILIVAVGII IANLISNFFR KTISKKTNDP
LMTNFLAKTI KISFSILVIM LALKIAGLGG IAAGLLTAAG ASAIIFGFAF KDVGENFISG
VILSFNRPFD VNDTVMIGDI FGKVKMMEFR FTKLKTFDGR DVYIPNSDIV KKAVYNYTED
GFYRSDFVVG IDYDDDIDTA KKVIINAVVN TLGVIDTDEH QCFVTVDGLG VSTVNLKVIF
WTKTKEYKRG ALEVKSDVIK NVKNVIIKNG LNMPADITEI KLYGSQDSIP VTVTK
//
