ID A0A1M5HII9_9FLAO Unreviewed; 929 AA.
AC A0A1M5HII9;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05444396_105114 {ECO:0000313|EMBL:SHG15632.1};
OS Flavobacterium segetis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=271157 {ECO:0000313|EMBL:SHG15632.1, ECO:0000313|Proteomes:UP000184036};
RN [1] {ECO:0000313|Proteomes:UP000184036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19741 {ECO:0000313|Proteomes:UP000184036};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FQWE01000005; SHG15632.1; -; Genomic_DNA.
DR RefSeq; WP_072990929.1; NZ_FQWE01000005.1.
DR AlphaFoldDB; A0A1M5HII9; -.
DR STRING; 271157.SAMN05444396_105114; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000184036; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 591..924
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 929 AA; 104151 MW; 13B96EF2E77421E3 CRC64;
MQVDLSQLDP KKNIIIKGAQ VHNLKNVDVA IPRNKLVVIT GLSGSGKSSL AFDTLYAEGQ
RRYVESLSSY ARQFLGRLDK PKVEYIKGIA PAIAIEQKVN TTNARSTVGT STEIYDYIKL
LFARIGRTYS PVSGREVKKN TVTDVVTDVK TFDLDSKWLL LAPIHLEEGR KLEDKLKVLL
QQGFARILVN NEMIRLDDLP DSLDKNDILL IVDRIVVKEE EEFYNRLADA VQTAFFEGKG
ICYLQELNAD KKYTYSNNFE LDGITFLEPN VHLFSFNNPY GACPICEGYG NIIGIDAELV
IPNTTLSVFE NAIFPWRGES MSYYRDELVN KAYKFDFPIH KPFFQLSEDQ KELIWSGNQY
FQGLNAFFKE LEEKNYKIQN RVMLSRYRGK TKCYSCKGKR LRVEASYVKI NSKTVSDLVD
LPIKHLVTFF QNIDLNVYEK QIAKRLLLEI NNRLSFLTEV GLDYLTLNRN SATLSGGESQ
RINLATSLGS SLVGSMYILD EPSIGLHPKD TERLIKVLLS LRDLGNTVIV VEHDEDIMKA
ADMIIDIGPE AGTLGGNLVA QGSYEEILKS TSLTAKYLNG DLEISVPKKR RTFKNYIEIK
GARENNLQNI DVTFPLDVLT VITGVSGSGK STLVKKILFP AMQKKLENIG EKAGQFSEIS
GSFSQIKHIE YVDQNPIGRS SRSNPVTYIK AYDDIRELYA REKLSKIRGY QAKHFSFNVD
GGRCETCKGE GSINVEMVFM ADVQLPCETC NGKRFKKEVL EVAFEGKNIN DILTMTVDDA
IAFFTAQKQA KIIQKLQPLQ DVGLGYVQLG QSSSTLSGGE AQRIKLASFL VKGVTKEKAL
FVFDEPTTGL HFHDIKKLLK SFDALIEKGH SIIVIEHNLD LIKCADWVID LGPEGGENGG
KLLAVGTPEE IVKNKKSVTA TYLKAALKK
//
