ID A0A1M5HZA2_9FLAO Unreviewed; 347 AA.
AC A0A1M5HZA2;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Uncharacterized zinc-type alcohol dehydrogenase-like protein {ECO:0000313|EMBL:SHG21331.1};
GN ORFNames=SAMN05444396_10622 {ECO:0000313|EMBL:SHG21331.1};
OS Flavobacterium segetis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=271157 {ECO:0000313|EMBL:SHG21331.1, ECO:0000313|Proteomes:UP000184036};
RN [1] {ECO:0000313|Proteomes:UP000184036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19741 {ECO:0000313|Proteomes:UP000184036};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR EMBL; FQWE01000006; SHG21331.1; -; Genomic_DNA.
DR RefSeq; WP_072991534.1; NZ_FQWE01000006.1.
DR AlphaFoldDB; A0A1M5HZA2; -.
DR STRING; 271157.SAMN05444396_10622; -.
DR OrthoDB; 9806940at2; -.
DR Proteomes; UP000184036; Unassembled WGS sequence.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05283; CAD1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR047109; CAD-like.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR PANTHER; PTHR42683:SF85; CINNAMYL ALCOHOL DEHYDROGENASE 6-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 13..342
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 347 AA; 37864 MW; 9B56913CF93DA3D8 CRC64;
MIQTKGYAVQ DKKTDLAPWS FERREVGPHD VQFDIQFCGV CHSDLHQIKD DWGGSIFPMV
PGHEIVGKVV KVGSHVKKFK VGDLAGTGCL VDSCRKCENC KEGLEQFCSN GSTGTYNALE
QDGKTPTYGG YSNTIVVHED FVLHISDKLD LAAVAPLLCA GITTYSPLRH WKVGKGHKLA
VLGLGGLGHM AVKFGVAFGA EVTVLSTSPE KEADAKKLGA HKFIVTKDAE QLKSVTGYFD
FILDTVSAPH DLNLYLSLLR VNGVHICVGV PPTPYEIHAF SLIGGRKSLA GSLIGGLPET
QEMLDYCAEH DIVSDIEMID IKNVHEAYDR MIKGDVRYRF VIDMATL
//
