ID A0A1M5I218_9FLAO Unreviewed; 1123 AA.
AC A0A1M5I218;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04488116_0364 {ECO:0000313|EMBL:SHG22069.1};
OS Allomuricauda flava.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Allomuricauda.
OX NCBI_TaxID=570519 {ECO:0000313|EMBL:SHG22069.1, ECO:0000313|Proteomes:UP000184532};
RN [1] {ECO:0000313|Proteomes:UP000184532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22638 {ECO:0000313|Proteomes:UP000184532};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FQWL01000001; SHG22069.1; -; Genomic_DNA.
DR RefSeq; WP_073176194.1; NZ_FQWL01000001.1.
DR AlphaFoldDB; A0A1M5I218; -.
DR STRING; 570519.SAMN04488116_0364; -.
DR OrthoDB; 1522078at2; -.
DR Proteomes; UP000184532; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43047:SF83; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF13424; TPR_12; 2.
DR Pfam; PF13181; TPR_8; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:SHG22069.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000313|EMBL:SHG22069.1}.
FT REPEAT 146..179
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 186..219
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 453..671
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 712..829
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 869..996
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REPEAT 1059..1092
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 406..449
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 762
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1123 AA; 126151 MW; C521419EA60FDB26 CRC64;
MAKGQHLIDS LQQLYPRAAS DSARILILKD ISWQYLNNRG NADLAKKHID SFHRLGERAN
FEWAVSLANY QYAVLERQKG NYNKALEHIE KYLDFHQGKN RAFAMANGLY QKAIILDDQG
KSDQSLEIYY SILAIYEEVG DSFGEATTYN AIGEIQKNTG KKSKAMESYE KALEIFERLD
DKTEIANCLF NIGDTHMQSQ DYDKALEHFH KALKLDQETQ SEWGQAYDYE ALGKVYALQK
NYTKSLEYHN WALALRKKLN QQMELSMSYS QIGAVQLQQK AYASAEQNLL TAIRISEEIG
AKSERQKNYG LLSQLYEATG DFERAIHHMN KFVSVKDSLF NEAKSKQIEE LQVRFDTQKK
QDAIATLQKD AEISELKLKQ QKTLRNIVIG ISIAALLLLY FAFNRYKNAQ RVKRAQEEKK
RAVVEERKRT EIEKQRVLEL QKIDKLKDEF LANTSHELRT PLVGIIGLTE SLTDGVAGKL
PKKAMDNLGM IATSGKRLAH LVNDILDFSK LKNKDLELST RPVDIYAVSN IVLQLSQPML
QDKKLKLINS IPKEISLVEA DENRLQQIIH NLIGNAIKFT PKGYITLLAE TKGKMLSVTV
SDTGIGIPED NLDRIFNSFE QGDGSTQREY GGTGLGLSVT KQLVELHGGE IRATSELGKG
SIFTFTLPLS SKTRKSLKLE KPSPSDFVLP LSTLNEEKVK IVGHQLSDEA PQVLIVDDEP
VNRRVLENHL TVAGYKVTEV SSGKEALKVL DDEHQFSLVL LDIMMPELSG YEVCKIVREH
SSASELPIIL LTAKNTVAEL VTGFEAGAND YLTKPFSKNE LLSRIKTHIN LNTIHKATSK
FVPTEFVQSV GKESITEVKL GDHIEKNVTV LFSDIRDYTS LAETMTPEQN FKFVNAYVGR
MGPIIKDNKG FVNQYLGDGI MAIFPKNAED ALDAAIEMQR TLALYNKRRV EEKGYQPLTV
GMGLHTGPLV MGIIGDSKRN DPAVIADTVN SGARVEGVTK YYGANIIISE GCLKSMKDSS
GFNFRYLGKV QVKGKQKAMG IYECIDSDPV DSITLKLESL KDYEMGIQLF FGQKFEEASE
KFEKILSLNP KDSVVEYFQN KAAIYAISGA PGDWQSVTVM NQK
//
