ID   A0A1M5I2V2_9FLAO        Unreviewed;       706 AA.
AC   A0A1M5I2V2;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=SAMN05444396_10699 {ECO:0000313|EMBL:SHG22596.1};
OS   Flavobacterium segetis.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=271157 {ECO:0000313|EMBL:SHG22596.1, ECO:0000313|Proteomes:UP000184036};
RN   [1] {ECO:0000313|Proteomes:UP000184036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19741 {ECO:0000313|Proteomes:UP000184036};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC       {ECO:0000256|ARBA:ARBA00005446}.
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DR   EMBL; FQWE01000006; SHG22596.1; -; Genomic_DNA.
DR   RefSeq; WP_072991700.1; NZ_FQWE01000006.1.
DR   AlphaFoldDB; A0A1M5I2V2; -.
DR   STRING; 271157.SAMN05444396_10699; -.
DR   OrthoDB; 9763310at2; -.
DR   Proteomes; UP000184036; Unassembled WGS sequence.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:InterPro.
DR   CDD; cd17920; DEXHc_RecQ; 1.
DR   CDD; cd18794; SF2_C_RecQ; 1.
DR   Gene3D; 1.10.150.80; HRDC domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR029491; Helicase_HTH.
DR   InterPro; IPR010997; HRDC-like_sf.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR044876; HRDC_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032284; RecQ_Zn-bd.
DR   InterPro; IPR018982; RQC_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR01389; recQ; 1.
DR   NCBIfam; TIGR00614; recQ_fam; 1.
DR   PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR   PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   Pfam; PF14493; HTH_40; 1.
DR   Pfam; PF16124; RecQ_Zn_bind; 1.
DR   Pfam; PF09382; RQC; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SMART; SM00956; RQC; 1.
DR   SUPFAM; SSF47819; HRDC-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SHG22596.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          27..193
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          214..362
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   DOMAIN          516..596
FT                   /note="HRDC"
FT                   /evidence="ECO:0000259|PROSITE:PS50967"
SQ   SEQUENCE   706 AA;  79887 MW;  834E86EDE4F0EBE2 CRC64;
     MTTAILHSTL KENFGFEKFR PNQEEIINCI LSGQDTLAIM PTGGGKSICF QLPALLFEGI
     TIVISPLIAL MKDQVDSLKA NGIEACFINS SQTENERQFY IESLKSNKIK LVYVAPESLS
     FLDNLFNTMT VSLIAIDEAH CISAWGHDFR PAYTNLGYLK NRFPSTPILA LTATADKATR
     KDISTQLNFV NPQIFVASFD RKNLSLEVRP ALDRVKQIID FIKDKPNESG IIYCLSRKTT
     EELAEKLQKT GINAKAYHAG LDGKIRSKTQ DQFINDDCQV VCATIAFGMG IDKSNVRWVI
     HYNLPKNIEG YYQEIGRAGR DGLPSETVLF ESYGDVIQLQ KFASQGLNAE VQLAKLERMK
     QYADALSCRR KILLSYFGEL VNDNCGNCDI CKNPPLFFDG TVIAQKALSA IIRLKESEPL
     AVIIDFLRGS KNAYIYEKEY QLLKTYAVGN DLSWFNWNQY LIQLINLGYC EIAFDQQNKI
     RLTAFAKKVL FEGEKVELTN VQKSIDKQQV KETKAKSSKN SLFEILRKLR YEISKEEEVP
     AYVIFSDAAL RQMETERPMS DEELLSIDGV GKAKLEKYGD SFIKAIIEFQ KAKVTKKKKE
     GTTYQETLEM YTSGLSIEAI AEKRKLGLST IMSHLAKLYS DGEAIDLSPF VSNNEVQKIA
     FAKNQLDSPE TLKPYFDYFE EKIDYGKIRL GLAIIEKKSF QFNKKI
//