ID A0A1M5K0H0_9FLAO Unreviewed; 1366 AA.
AC A0A1M5K0H0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05443549_104137 {ECO:0000313|EMBL:SHG46175.1};
OS Flavobacterium fluvii.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=468056 {ECO:0000313|EMBL:SHG46175.1, ECO:0000313|Proteomes:UP000184516};
RN [1] {ECO:0000313|Proteomes:UP000184516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19978 {ECO:0000313|Proteomes:UP000184516};
RA Varghese N., Submissions S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FQWB01000004; SHG46175.1; -; Genomic_DNA.
DR RefSeq; WP_073370450.1; NZ_FQWB01000004.1.
DR STRING; 468056.SAMN05443549_104137; -.
DR OrthoDB; 1522078at2; -.
DR Proteomes; UP000184516; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 4.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 3.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Kinase {ECO:0000313|EMBL:SHG46175.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000184516};
KW Transferase {ECO:0000313|EMBL:SHG46175.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 794..814
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 848..1068
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1115..1230
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1262..1361
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1163
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1366 AA; 155221 MW; A669D0F688D9DCA5 CRC64;
MKHTLFLLSF LLITIGVSSQ TNKYRLNNLS TVDGLSQSSV IAIRQDAIGQ MWFGTRDGLN
KYDGSRFTIY RNDPTDSTSI SNNDILALEE DKSGKMWVGT YNGLNCYNPV KNSFKQYFHA
NNDNSLCNNT VWSIKEIKNE IWIGTSRGLS IYNKTTNKFI TVFHSSRNKS SLSNNFVLSI
LETKSGTIWI GTAKGLCKLT SRKKGVFLFQ EFNRPDNGES LFVQSLKEDV AGNLWIGTKT
SGLYKFDAVS KKLISLLANG KQNGIDVDVR SIDIDRKGAL WIGAYNGVSV MQKDGAIQKI
FNNPDKKTNI TKIKSVFTDK KGSVWIGTYY NGVDIWDVSN INFTNLNQES GKRALSFDVV
SSIVADKDKN IYFGTEGGGI TILDNKTETT SYLTANKSSE LSRNNIKSMF LSDKGILWIG
TFSEGLEAYD IKSKRFINED IAPDLRKLLR ESGVYVIKKG RKNDILWLGT FGKGLIRYDS
SNKTYQVMGN DNYSDNFLSN NRIRTLLVDK KDNIWIGTQS GLNLINLNDL DNNNYQIKHF
FFDNKVLSGD DILALFQDKK NRIWVGTKAK GLYLFNGKTF NKINISVGNS AITSIHSISE
DSKNNLWLSS NYGIIKYNPS RNSVIVYDQK DGLVSNEFND NAFLQLDSHK FYFGGPLGVS
YFDSNLIALN SYSPQVILTN FKIKNESVNV NANQDILEKS IAYTKSLTLS YDKANISINF
AIPNFINSTN NQYSYRLVGL ENNWTTTANT EAVYTIQKPG TYLFEVKGAN NDGVWNKTPT
TLEIIVEPAP WRSWWAFLFY FLLIGTGLYG LIWIMKSKEN LKKELEFEYM EGEINKENTL
AKLQFFTNIS HEFRTPLTLI LGPLQQILSN YNGTNEMYKK LLVIESSANH LLSLINRLMD
FRKFENNQFV LESAEGNIVK FLNEIFLSFT EYAKDGNYTY TFSTSDEEIL VYYDRYKLER
VFYNLISNAF RYTPKGGVIS IHIKKEEKDI VIEVEDSGVG IAEENIAKIF DLFFEIPTHK
NVETNYSKGT GIGLSIAKNI VELHHGTIDV KNKDAKGVVF KVALPLGKEH LSEKEILLDF
KISDDVSQYS AQLENQEIIQ DDDVSDLMVH EDKLTILIVE DHKVLRSFMK NLLKKEYNII
EAENGKKGLK KALEHVPDLI ISDVIMPEMV GTELCAKVKE NLKTSHIPVI LLTSRSSLIY
KIEGLENGAD DYISKPFNLK EFKLRIKNLL DSTQRLKAKF SSDDSFSPSE ITVSSLDEQL
LKKAFKLVEE NIANEQFDIP FFSAELGVSR TMLFTKIKAW TNFTPNEFIH EVRMKRAAQL
LEQNKMNVSQ ISYKVGFNNP KYFSKCFQKK YGETPSQYAN KFSEDS
//
