ID A0A1M5K831_9BACT Unreviewed; 397 AA.
AC A0A1M5K831;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=23S rRNA (Cytosine1962-C5)-methyltransferase {ECO:0000313|EMBL:SHG48976.1};
GN ORFNames=SAMN05720761_102197 {ECO:0000313|EMBL:SHG48976.1};
OS Fibrobacter sp. UWCM.
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=1896208 {ECO:0000313|EMBL:SHG48976.1, ECO:0000313|Proteomes:UP000184289};
RN [1] {ECO:0000313|EMBL:SHG48976.1, ECO:0000313|Proteomes:UP000184289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UWCM {ECO:0000313|EMBL:SHG48976.1,
RC ECO:0000313|Proteomes:UP000184289};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
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DR EMBL; FQWR01000002; SHG48976.1; -; Genomic_DNA.
DR RefSeq; WP_072810033.1; NZ_FQWR01000002.1.
DR AlphaFoldDB; A0A1M5K831; -.
DR Proteomes; UP000184289; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SHG48976.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHG48976.1}.
FT DOMAIN 2..86
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 397 AA; 44503 MW; AA6DD2B13E4BC7BB CRC64;
MKAITLKAGR EKSALRYHPW IFSGAVDEVV GDPELGDTVE VYSYRSDFLG LAAYSPKSQI
RGRFWTFGEK ANIDREFFSD ILDRAIAARK SRGFDIEDKE SAFRLINAEN DGIPGCIIDK
YADIYSVEIL AAGAEVHRET IYELLAEKTH CKGIYERCDS EVRRKEGLQL RTGVVYGEVS
DEPVIINENG ILFPIDVKNG HKTGYYLDQR DARRRIGELS KGKKVLNCFC YTGGFGLYAL
RGGCEKVYQV DVSKDALKLA KEGIMRNKLS TAHATHVEAD VFQYLRKCRD KAETFDLIVL
DPPKFVESKD NLQKGARGYK DINLLAMKLL AEGGMLATFS CSGLMEMDLF QKIIADAAAD
AHRRVQIIER FGQPADHPVN TAFPEGQYLK GLLVQVV
//
