ID A0A1M5KL84_9ACTN Unreviewed; 393 AA.
AC A0A1M5KL84;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Acetyl-CoA acetyltransferases {ECO:0000313|EMBL:SHG53612.1};
GN ORFNames=SAMN05443575_2195 {ECO:0000313|EMBL:SHG53612.1};
OS Jatrophihabitans endophyticus.
OC Bacteria; Actinomycetota; Actinomycetes; Jatrophihabitantales;
OC Jatrophihabitantaceae; Jatrophihabitans.
OX NCBI_TaxID=1206085 {ECO:0000313|EMBL:SHG53612.1, ECO:0000313|Proteomes:UP000186132};
RN [1] {ECO:0000313|EMBL:SHG53612.1, ECO:0000313|Proteomes:UP000186132}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45627 {ECO:0000313|EMBL:SHG53612.1,
RC ECO:0000313|Proteomes:UP000186132};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FQVU01000003; SHG53612.1; -; Genomic_DNA.
DR RefSeq; WP_073390019.1; NZ_FQVU01000003.1.
DR AlphaFoldDB; A0A1M5KL84; -.
DR STRING; 1206085.SAMN05443575_2195; -.
DR OrthoDB; 1402717at2; -.
DR Proteomes; UP000186132; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF134; BETA-KETOACYL COA THIOLASE FADA3-RELATED; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000186132};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SHG53612.1}.
FT DOMAIN 7..260
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..389
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 347
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 377
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 393 AA; 40633 MW; 0B81A225D35CB3C2 CRC64;
MSAFLYDAVR TPFGRFNGAL AAVRPDNLAA TALGALLART PALDPADVDD VVFGLANGAG
EDNRNLGRMA ALLAGLPTSV PGSTVNRLCG SSLDATMIAS RAIETGDADV VVAGGAESMT
RAPWVLPKPD KAFPVANVTA VSTALGWRLV NPAMPEEWTI SLGEANEQLQ EKFGISRERQ
DEFAARSHQR ADAAWDDGFY DPLVVPVPGV ELPRDEGIRP GSTAEKLAAL KPSFRKDGTI
TAGNASPLND GAGALLVGSE AAAGRLGREP VARIAGRGAF ALDPRDFGYA PVEAANRALA
RAGIGWDDVS AVELNEAFAV QSLACVDGWK IDPDIVNTRG GAIAIGHPLG ASGTRILGTL
AEVLRRDGGR WGVAAICIGV GQGLAIVLEN VSS
//
