ID   A0A1M5L044_9FLAO        Unreviewed;       294 AA.
AC   A0A1M5L044;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:SHG58482.1};
GN   ORFNames=SAMN05443549_10526 {ECO:0000313|EMBL:SHG58482.1};
OS   Flavobacterium fluvii.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=468056 {ECO:0000313|EMBL:SHG58482.1, ECO:0000313|Proteomes:UP000184516};
RN   [1] {ECO:0000313|Proteomes:UP000184516}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19978 {ECO:0000313|Proteomes:UP000184516};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC       {ECO:0000256|ARBA:ARBA00009405}.
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DR   EMBL; FQWB01000005; SHG58482.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M5L044; -.
DR   STRING; 468056.SAMN05443549_10526; -.
DR   Proteomes; UP000184516; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR   CDD; cd07938; DRE_TIM_HMGL; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR043594; HMGL.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:SHG58482.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184516}.
FT   DOMAIN          10..280
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   294 AA;  32836 MW;  723BECDEA5243192 CRC64;
     MPYLWFSMEA IKLIECPRDA MQGIKTFIPT ARKVSYIQSL LRVGFDTIDF GSFVSPKAIP
     QMQDTAEVLA QLDLSQTQSK LLAIIANTQG AIAASQHKSI QYLGFPFSIS ENFQMRNTHK
     TIAESVITLE EIMEIAEKSN KEVVAYLSMG FGNPYGDPWN VEIVGEWTEK LSNMGVKILS
     LSDTVGSSTP EVIQYLFSHL IPKYPKIEFG AHLHTTPDKW FEKMDAAYNS GCRRFDGAIQ
     GFGGCPMAKD ILTGNMPTEK LVSYFTSKKE NTNVSAMSFE SAYNEATKIF KAFH
//