ID A0A1M5LEV8_9FLAO Unreviewed; 429 AA.
AC A0A1M5LEV8;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Hemolysin, contains CBS domains {ECO:0000313|EMBL:SHG63662.1};
GN ORFNames=SAMN05444148_0603 {ECO:0000313|EMBL:SHG63662.1};
OS Winogradskyella jejuensis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Winogradskyella.
OX NCBI_TaxID=1089305 {ECO:0000313|EMBL:SHG63662.1, ECO:0000313|Proteomes:UP000184522};
RN [1] {ECO:0000313|EMBL:SHG63662.1, ECO:0000313|Proteomes:UP000184522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25330 {ECO:0000313|EMBL:SHG63662.1,
RC ECO:0000313|Proteomes:UP000184522};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FQWS01000001; SHG63662.1; -; Genomic_DNA.
DR RefSeq; WP_073082838.1; NZ_FQWS01000001.1.
DR AlphaFoldDB; A0A1M5LEV8; -.
DR STRING; 1089305.SAMN05444148_0603; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000184522; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF33; UPF0053 PROTEIN YEGH; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..200
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 279..342
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 429 AA; 48914 MW; 0EEB29FE375CB0CC CRC64;
MSTNALIIVG SLILSAFFSG MEIAYVSSNK IHIELEKKQG DFLGKLLSKL TARPSKFITT
MLIGNNIALV IYGFVMGDVL VSWFQGFLPS EYTVVNYLLD ELQLLSQTVI STMIILLTAE
FLPKVFFQIY SNTLLKFFAL PAYIFYIVFS FISEFVIRIS DFVLKTFFKT EGDAVEIALT
KVELGNFITE QMESVEEHDE VDSEIQIFQN ALEFTEVKAR EVMVPRTEIT AVDISDTVEN
LRQIFIETGY TKILVYKDSI DDILGYVHSF ELFKKPKTIK SILIPVVYVP ETIRIKDVLN
LLTKKRKSIA VVIDEYGGTS GMMTVEDIIE ELFGEIEDEH DSVELTEEQL TENSYNFSAR
LEVDYLNETY KLNLPESEAY ETLGGLIVNH TEDIPKINES IKIDNFKFKI TEVSSTKIDN
VYLEIIEPE
//
