ID   A0A1M5LYK0_9BACT        Unreviewed;       978 AA.
AC   A0A1M5LYK0;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE            EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN   ORFNames=SAMN04488109_1469 {ECO:0000313|EMBL:SHG70172.1};
OS   Chryseolinea serpens.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Fulvivirgaceae;
OC   Chryseolinea.
OX   NCBI_TaxID=947013 {ECO:0000313|EMBL:SHG70172.1, ECO:0000313|Proteomes:UP000184212};
RN   [1] {ECO:0000313|EMBL:SHG70172.1, ECO:0000313|Proteomes:UP000184212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24574 {ECO:0000313|EMBL:SHG70172.1,
RC   ECO:0000313|Proteomes:UP000184212};
RA   Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC         in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|ARBA:ARBA00001412};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
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DR   EMBL; FQWQ01000001; SHG70172.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1M5LYK0; -.
DR   STRING; 947013.SAMN04488109_1469; -.
DR   Proteomes; UP000184212; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR46323:SF2; BETA-GALACTOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:SHG70172.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000184212}.
FT   DOMAIN          61..237
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          256..363
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          370..514
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
SQ   SEQUENCE   978 AA;  109281 MW;  EBF81A30BDA5D24D CRC64;
     MKNNKTVTMR KEEPVLSLHG MEKSEKNPTR QITRHASLLL VILLALSART FGQPNPATLD
     LSGQWSFQID RKDEGVEGKW FTKPLNDHIM LPGSMASNGK GDDIAVNTPW TGSIFDSAFF
     KSPEFAPYRQ PGNIKVPFWL QPVKYFKGVA WYQKTITLPP SWGDKFVELF IERAHWETTV
     WIDDVPLGQQ NSLAVSHVYV LPAKIRPGVH RISIRVDNRV KQIDVGQNSH SISDHTQTNW
     NGMIGKLQLQ AKPLIYVHNV KIFPNLKDQK LLVRVQLINT THQKAKATLE LQARPTASQT
     SNLKKISKAL EVQPDSSVVE IEYHMGNAPL LWDEFNPNRY VLTVNLSHEK GKADVKDVDF
     GMREFSSSGT QFTINGRPVF LRGTLECAIF PKTGFPPTDK AAWTNVFVTC KAFGLNHVRF
     HSWCPPESAF DVADSLGIYV QIECSSWANQ GSAVGDGKPV DRYILQESER IVNAYGNHPS
     FCLMAYGNEP AGDHQVKYLT DFVNYWKQHD NRRQYTTGAG WPLVPENNYN STPDPRIQHW
     GAGLKSIING KAPATNYDWS GIINQWPIPT VSHEIGQWCV FPDLKEIAQY DGVLKAKNFE
     IFEATLKKNN LRHLADSFLL ASGKLQALCY KADIEAALRT KNFAGFQLLD LHDFPGQGTA
     LVGVLNPFWK EKGYITAKEY SRFCNAIVPL ARFSKMIYWN DEALDVPVEV ANFSNGALNA
     GAATWEIADR SGKVIFKGDF PKAIIPVGNG NELGHIKQTL TQIAAPSFLI LTVSVGAVQN
     SWDFFVYPAK HSEGTDEILV TDHLDKRAVD ALNQGGKVIL TPRKGSVKPE FGGDIAVGFS
     SIFWNTAWTN GQPPHTLGIL CNPQHPAFAL FPTQYHSNWQ WWDAMSHSNA ILLDAVDPGL
     HPIVRVVDDW VTSRSIGLLF ECSVGKGTLI VSGIDLLTDQ EQRPEARQLL LSLKNYLHQK
     SSRPSLAISP EKIAGIFK
//