ID A0A1M5M2Z0_9GAMM Unreviewed; 427 AA.
AC A0A1M5M2Z0;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:SHG71600.1};
GN ORFNames=SAMN04488068_1233 {ECO:0000313|EMBL:SHG71600.1};
OS Hydrocarboniphaga daqingensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Nevskiales; Nevskiaceae;
OC Hydrocarboniphaga.
OX NCBI_TaxID=490188 {ECO:0000313|EMBL:SHG71600.1, ECO:0000313|Proteomes:UP000199758};
RN [1] {ECO:0000313|EMBL:SHG71600.1, ECO:0000313|Proteomes:UP000199758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7049 {ECO:0000313|EMBL:SHG71600.1,
RC ECO:0000313|Proteomes:UP000199758};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|RuleBase:RU003557}.
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DR EMBL; FQWZ01000002; SHG71600.1; -; Genomic_DNA.
DR RefSeq; WP_072895320.1; NZ_FQWZ01000002.1.
DR AlphaFoldDB; A0A1M5M2Z0; -.
DR STRING; 490188.SAMN04488068_1233; -.
DR OrthoDB; 1402717at2; -.
DR Proteomes; UP000199758; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR42689; ACETYL-COA ACYLTRANSFERASE FADA2 (3-KETOACYL-COA THIOLASE) (BETA-KETOTHIOLASE)-RELATED; 1.
DR PANTHER; PTHR42689:SF1; ACETYL-COA ACYLTRANSFERASE FADA2 (3-KETOACYL-COA THIOLASE) (BETA-KETOTHIOLASE)-RELATED; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000199758};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SHG71600.1}.
FT DOMAIN 8..276
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 301..427
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 92
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 384
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 414
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 427 AA; 45835 MW; 0E482FD95405BF6D CRC64;
MSTYGRRVAL LGGARIPFAR SNTVYSYKSN QEMLTAALRG VVDKYQLQGE RLGEVAAGAV
LKHSRDFNLT RECVLSSGLA AETPAYDIQQ ACGTGLEAAI LVGNKIAMGQ IESGIAGGVD
TASDAPIAVG DKLRTLLLDL NRAKTNSQRL QILTRFRPSM LAPSAPTNGE PRTRKSMGEH
CEMMAQEWKI SREDQDLLAV ESHLKAAKAY DEGFFDDLLV EFAGVKRDNN LRGDSKIEKL
ATLKPVFDRK SGKGTLTAAN STPLTDGASA ALLSSEAWAD AHGFKPQAFL THSETAAVDF
TVKKEGLLMA PVYAVPRMLE RAGLTLQDFD FYEIHEAFAA QVLCTLRAWE DAKYCKERLG
LAKPLGSIDR SKLNVKGSSL ALGHPFAATG GRILATAGKL LEQRGGGRCL ISICAAGGMG
VVAIVER
//
